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1. (WO2017151042) PHARMACEUTICAL COMPOSITIONS FOR ON DEMAND ANTICOAGULANT THERAPY

Pub. No.:    WO/2017/151042    International Application No.:    PCT/SE2017/050179
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Tue Feb 28 00:59:59 CET 2017
IPC: A61K 9/70
A61K 31/4402
A61K 47/22
A61K 47/26
A61P 7/02
Applicants: KENOX PHARMACEUTICALS INC
Inventors: JOGUPARTHI, Vijay
VELAGA, Sitaram
Title: PHARMACEUTICAL COMPOSITIONS FOR ON DEMAND ANTICOAGULANT THERAPY
Abstract:
A pharmaceutical composition for adminstration of Dabigatran etexilate through the mucous membranes of the oral cavity, characterized in that the composition comprises a therapeutically effective amount of Dabigatran etexilate and a solubilizer for Dabigatran etixilate selected from at least one of a water soluble derivative of tocopherol and a polymeric derivative of sorbitan. The composition may be in the form of solid oral film. The composition may be suitable for dropwise administration. A method of manufacturing the film composition is also included.