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1. (WO2017150763) ANIMAL MODEL EXPRESSING HUMAN CD3 AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2017/150763 International Application No.: PCT/KR2016/003358
Publication Date: 08.09.2017 International Filing Date: 31.03.2016
IPC:
A01K 67/027 (2006.01) ,C12N 15/85 (2006.01) ,C07K 14/725 (2006.01) ,G01N 33/50 (2006.01)
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
K
ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67
Rearing or breeding animals, not otherwise provided for; New breeds of animals
027
New breeds of vertebrates
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
85
for animal cells
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
725
T-cell receptors
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
Applicants:
(주)메디톡스 MEDYTOX INC. [KR/KR]; 충청북도 청주시 청원구 오창읍 각리1길 78 78, Gangni 1-gil Ochang-eup, Cheongwon-gu Cheongju-si Chungcheongbuk-do 28126, KR
Inventors:
김선택 KIM, Sun Taek; KR
류기혁 RYU, Gi Hyuck; KR
박상래 PARK, Sang Rae; KR
곽성성 KWAK, Seong Sung; KR
정현호 JUNG, Hyun Ho; KR
양기혁 YANG, Gi Hyeok; KR
Agent:
이처영 LEE, Cheo Young; KR
Priority Data:
10-2016-002457629.02.2016KR
Title (EN) ANIMAL MODEL EXPRESSING HUMAN CD3 AND USE THEREOF
(FR) MODÈLE ANIMAL EXPRIMANT CD3 HUMAIN ET SON UTILISATION
(KO) 인간 CD3 발현 동물모델 및 이의 용도
Abstract:
(EN) The present invention relates to an animal model expressing human CD3 and a use thereof, and more specifically, to: an animal model into which a gene encoding human CD3 has been introduced; a method for producing the animal model; and a method for screening a therapeutic agent for T cell-mediated diseases using the animal model.
(FR) La présente invention se rapporte à un modèle animal exprimant CD3 humain et une utilisation de celui-ci, et plus particulièrement à : un modèle animal dans lequel un gène codant pour CD3 humain a été introduit; elle se rapporte également à un procédé de production de ce modèle animal, ainsi qu'à un procédé de criblage d'un agent de thérapie de maladies à médiation lymphocytaire T, à l'aide du modèle animal.
(KO) 본 발명은 인간 CD3 발현 동물모델 및 이의 용도에 관한 것으로, 구체적으로는 인간 CD3를 코딩하는 유전자가 도입되어 있는 동물모델, 상기 동물모델의 제조방법 및 상기 동물모델을 이용하여 T세포 매개 질환 치료제를 스크리닝하는 방법에 관한 것이다.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)