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|1. (WO2017150681) AMYOTROPHIC LATERAL SCLEROSIS DIAGNOSTIC METHOD USING SIGNAL PEPTIDE AS INDEX|
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY
|Title:||AMYOTROPHIC LATERAL SCLEROSIS DIAGNOSTIC METHOD USING SIGNAL PEPTIDE AS INDEX|
This method assists in the detection of ALS and involves determining the profile of signal peptides contained in a bodily fluid derived from a subject being examined, and comparing said determined signal peptide profile of the subject being examined with the profile of signal peptides in the bodily fluid derived from a pre-determined healthy subject. Further, this method is characterized in that a difference at a specific molecular weight between the signal peptide profile of the subject being examined and the signal peptide profile of the healthy subject is associated with the subject being examined suffering from or developing ALS.