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1. (WO2017149546) MULTI DRUG COMPOSITE, PREPARATION METHODS AND USES THEREOF

Pub. No.:    WO/2017/149546    International Application No.:    PCT/IL2017/050269
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Fri Mar 03 00:59:59 CET 2017
IPC: A61K 9/51
A61K 47/02
A61K 31/00
Applicants: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD
Inventors: WILLNER, Itamar
HELEG-SHABTAI, Vered
AIZEN, Ruth
ETERY, Sharon
ENKIN, Natalie
Title: MULTI DRUG COMPOSITE, PREPARATION METHODS AND USES THEREOF
Abstract:
The invention provides mesoporous nanoparticles loaded within its pores with at least one loaded pharmaceutically active agent and at least one capping pharmaceutically active agent chemically coordinated with at least one ligand being boronic acid or derivative thereof on the surface of said pores; compositions comprising such mesoporous nanoparticles and uses thereof.