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1. (WO2017149546) MULTI DRUG COMPOSITE, PREPARATION METHODS AND USES THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/149546 International Application No.: PCT/IL2017/050269
Publication Date: 08.09.2017 International Filing Date: 02.03.2017
IPC:
A61K 9/51 (2006.01) ,A61K 47/02 (2006.01) ,A61K 31/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
51
Nanocapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
02
Inorganic compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
Applicants:
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD [IL/IL]; Hi Tech Park Edmond J. Safra Campus Givat Ram 91390 Jerusalem, IL
Inventors:
WILLNER, Itamar; IL
HELEG-SHABTAI, Vered; IL
AIZEN, Ruth; IL
ETERY, Sharon; IL
ENKIN, Natalie; IL
Agent:
COHEN, Mark; Pearl Cohen Zedek Latzer Baratz P.O. Box 7198 6107121 Tel Aviv, IL
Priority Data:
62/302,89503.03.2016US
Title (EN) MULTI DRUG COMPOSITE, PREPARATION METHODS AND USES THEREOF
(FR) COMPOSITE MULTI-MÉDICAMENTS, SES PROCÉDÉS DE PRÉPARATION ET SES UTILISATIONS
Abstract:
(EN) The invention provides mesoporous nanoparticles loaded within its pores with at least one loaded pharmaceutically active agent and at least one capping pharmaceutically active agent chemically coordinated with at least one ligand being boronic acid or derivative thereof on the surface of said pores; compositions comprising such mesoporous nanoparticles and uses thereof.
(FR) L'invention concerne des nanoparticules mésoporeuses dont les pores sont chargés d'au moins un agent pharmaceutiquement actif chargé et d'au moins un agent pharmaceutiquement actif coiffant chimiquement coordonné avec au moins un ligand qui est l'acide boronique ou un dérivé de celui-ci à la surface desdits pores ; des compositions comprenant ces nanoparticules mésoporeuses et leurs utilisations.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
IL261539EP3423043US20190060247CN109562078