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1. (WO2017149515) CELLS EXPRESSING MULTIPLE CHIMERIC ANTIGEN RECEPTOR (CAR) MOLECULES AND USES THEREFORE

Pub. No.:    WO/2017/149515    International Application No.:    PCT/IB2017/051267
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Sat Mar 04 00:59:59 CET 2017
IPC: C07K 14/725
C07K 16/30
C12N 5/0783
Applicants: NOVARTIS AG
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
Inventors: DRANOFF, Glenn
Title: CELLS EXPRESSING MULTIPLE CHIMERIC ANTIGEN RECEPTOR (CAR) MOLECULES AND USES THEREFORE
Abstract:
The invention provides compositions and methods for treating diseases associated with expression of a tumor antigen as described herein by administration of a cell comprising a chimeric antigen receptor that binds a B-Cell antigen and a chimeric antigen receptor which binds a tumor antigen.