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1. (WO2017149513) ANTI-MCAM ANTIBODIES AND ASSOCIATED METHODS OF USE

Pub. No.:    WO/2017/149513    International Application No.:    PCT/IB2017/051264
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Sat Mar 04 00:59:59 CET 2017
IPC: A61K 39/395
C07K 16/30
Applicants: PROTHENA BIOSCIENCES LIMITED
Inventors: NESS, Daniel Keith
FLANAGAN, Kenneth
Title: ANTI-MCAM ANTIBODIES AND ASSOCIATED METHODS OF USE
Abstract:
The invention provides anti-MCAM antibodies that inhibit the ability of human MCAM to bind a laminin alpha-4 chain, dosage regimes, monitoring regimes, and treatment regimes with agent inhibiting MCAM expression.