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1. (WO2017149463) CYANO-SUBSTITUTED INDOLE COMPOUNDS AND USES THEREOF AS LSD1 INHIBITORS

Pub. No.:    WO/2017/149463    International Application No.:    PCT/IB2017/051181
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Wed Mar 01 00:59:59 CET 2017
IPC: C07D 401/04
C07D 401/06
C07D 403/04
C07D 405/04
C07D 405/06
C07D 209/14
A61K 31/404
A61P 35/00
Applicants: NOVARTIS AG
Inventors: DU-CUNY, Lei
XIAO, Qitao
XUN, Guoliang
ZHENG, Qiangang
HE, Feng
Title: CYANO-SUBSTITUTED INDOLE COMPOUNDS AND USES THEREOF AS LSD1 INHIBITORS
Abstract:
A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for the treatment of lysine (K)-specific demethylase 1A (LSD1) - mediated diseases or disorders: (I) wherein R1, R2, R3, R4, R5, and R6 are as defined herein.