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1. (WO2017148977) PRODRUGS OF THE SELECTIVE PROGESTERONE RECEPTOR MODULATOR (SPRM) (11.BETA.,17.BETA.)-17-HYDROXY-11-[4-(METHYLSULPHONYL)PHENYL]-17-(PENTAFLUOROETH YL)ESTRA-4,9-DIEN-3-ONE

Pub. No.:    WO/2017/148977    International Application No.:    PCT/EP2017/054704
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Thu Mar 02 00:59:59 CET 2017
IPC: C07J 31/00
A61K 31/567
A61P 5/36
Applicants: BAYER PHARMA AKTIENGESELLSCHAFT
Inventors: MILITZER, Hans-Christian
ROTTMANN, Antje
WAGENFELD, Andrea
IRLBACHER, Horst
Title: PRODRUGS OF THE SELECTIVE PROGESTERONE RECEPTOR MODULATOR (SPRM) (11.BETA.,17.BETA.)-17-HYDROXY-11-[4-(METHYLSULPHONYL)PHENYL]-17-(PENTAFLUOROETH YL)ESTRA-4,9-DIEN-3-ONE
Abstract:
This invention concerns Selective Progesterone Receptor Modulators (SPRM) in a prodrug form as well as their application in therapy. (3α, 11β,17β)-1 1-[4-(methylsulfonyl)phenyl]-17-(pentafluoroethyl)estra-4,9-diene-3,17-diol (Compound 1) is one of the invention prodrugs.