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1. (WO2017148967) NEW DIFLUOROKETAMIDE DERIVATIVES AS HTRA1 INHIBITORS

Pub. No.:    WO/2017/148967    International Application No.:    PCT/EP2017/054682
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Thu Mar 02 00:59:59 CET 2017
IPC: C07K 5/02
A61K 38/06
A61P 27/02
Applicants: F. HOFFMANN-LA ROCHE AG
HOFFMANN-LA ROCHE INC.
Inventors: MAERKI, Hans P.
HORNSPERGER, Benoit
MOHR, Peter
REUTLINGER, Michael
IACONE, Roberto
Title: NEW DIFLUOROKETAMIDE DERIVATIVES AS HTRA1 INHIBITORS
Abstract:
The invention provides novel compounds having the general formula (I) wherein wherein R1, R2, R3, R4, R5, R6, R7, R3, R8, R9, R10, R11, R12 and R23 are as described herein, compositions including the compounds and methods of using the compounds.