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1. (WO2017148519) PYRIDINYLMETHYL CARBAMIMIDOYLCARBAMATE DERIVATIVES AND THEIR USE AS AOC3 INHIBITORS

Pub. No.:    WO/2017/148519    International Application No.:    PCT/EP2016/054541
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Fri Mar 04 00:59:59 CET 2016
IPC: C07D 213/72
C07D 213/82
C07D 401/04
C07D 401/12
C07D 401/14
C07D 405/14
A61K 31/4545
A61K 31/496
A61K 31/506
A61P 1/16
A61P 13/12
A61P 27/02
C07D 213/80
C07D 213/84
C07D 213/85
C07D 239/42
C07D 413/14
C07D 417/12
C07D 417/14
C07D 451/02
C07D 487/08
Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Inventors: HIMMELSBACH, Frank
BLUM, Andreas
PETERS, Stefan
Title: PYRIDINYLMETHYL CARBAMIMIDOYLCARBAMATE DERIVATIVES AND THEIR USE AS AOC3 INHIBITORS
Abstract:
The invention relates to new heteroaryl derivatives of the formula wherein X1 is selected from the group consisting of: N and CH; X2 is selected from the group consisting of: N and CF; (whith the proviso that at least one of X1 and X2 is N), and A is as defined in the description and claims, to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.