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|1. (WO2017148455) IODINATED ANALOGS OF CHOLINE, METHODS OF PREPARATION THEREOF, AND USE THEREOF AS MEDICAMENTS|
|Applicants:||UNIVERZITA PALACKEHO V OLOMOUCI
|Title:||IODINATED ANALOGS OF CHOLINE, METHODS OF PREPARATION THEREOF, AND USE THEREOF AS MEDICAMENTS|
The invention relates to iodinated aromatic choline analogs of general formula wherein at least one R is iodine; the quaternary ammonium group comprises a hydroxyl substituent, and further substituent are as defined in the claims. The compounds of the invention can be used in medicine as imaging agents and therapeutics, in particular in oncologic, inflammatory and neurological disorders.