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1. (WO2017148426) METHOD FOR DETERMINING FINGERPRINT OF CHINESE MEDICINE COMPOSITION

Pub. No.:    WO/2017/148426    International Application No.:    PCT/CN2017/075513
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Sat Mar 04 00:59:59 CET 2017
IPC: G01N 30/02
Applicants: SHIJIAZHUANG YILING PHARMACEUTICAL CO., LTD.
石家庄以岭药业股份有限公司
Inventors: BI, Dan
毕丹
CHEN, Yupeng
陈育鹏
ZHAO, Qian
赵倩
YE, Yuting
叶玉廷
ZHANG, Shuiying
张水英
REN, Jin
任晋
WEI, Feng
魏峰
Title: METHOD FOR DETERMINING FINGERPRINT OF CHINESE MEDICINE COMPOSITION
Abstract:
Provided is a method for determining a high-performance liquid chromatographic fingerprint of a Chinese medicine composition. The Chinese medicine composition consists of forsythia, Japanese honeysuckle, indigowoad root, bitter almond, mentha-camphor, houttuynia cordata, rhubarb, patchouli, male fern rhizome, kirilow rhodiola root and rhizome, ephedra, licorice, and gypsum. The fingerprint determination method detects 15 main chromatographic peaks, and identifies nine of the main chromatographic peaks as neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, isoforsythiaside A, forsythiaside A, forsythin, quercitrin, 4,5-di-O-caffeoylquinic acid, and glycyrrhizic acid ammonium salt, respectively.