Search International and National Patent Collections

1. (WO2017148357) SACUBITRIL INTERMEDIATE AND PREPARATION METHOD THEREOF

Pub. No.:    WO/2017/148357    International Application No.:    PCT/CN2017/075097
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Wed Mar 01 00:59:59 CET 2017
IPC: C07C 59/84
C07C 69/738
C07C 49/245
C07C 49/255
C07C 235/78
C07D 498/04
C07C 51/09
C07C 233/47
C07C 231/02
C12P 13/00
Applicants: SUNSHINE LAKE PHARMA CO., LTD.
广东东阳光药业有限公司
Inventors: CHEN, Lei
陈磊
SUN, Guodong
孙国栋
HAN, Xiaodong
韩小东
LI, Shun
李顺
ZENG, Jiebin
曾洁滨
WANG, Zhongqing
王仲清
LUO, Zhonghua
罗忠华
Title: SACUBITRIL INTERMEDIATE AND PREPARATION METHOD THEREOF
Abstract:
The present invention relates to a sacubitril intermediate and a preparation method thereof. The sacubitril intermediate can be prepared by subjecting a compound to a deprotection reaction. The intermediate can be used as a raw material and further synthesized to form a sacubitril compound. The method provided by the invention has the advantages of easily acquired raw materials, simple techniques, cost effectiveness, and environmental friendliness, and is therefore suitable for industrial production.