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1. (WO2017148099) WOUND DRESSING AND PREPARATION METHOD THEREFOR

Pub. No.:    WO/2017/148099    International Application No.:    PCT/CN2016/092998
Publication Date: Sat Sep 09 01:59:59 CEST 2017 International Filing Date: Thu Aug 04 01:59:59 CEST 2016
IPC: A61F 13/00
A61L 15/00
Applicants: GUANGZHOU DIANFANG BIOTECH CO.,LTD
广州市电纺生物科技有限公司
Inventors: WAN, Huayin
万华印
ZHANG, Junhui
张俊辉
HE, Ting
何婷
LI, Weida
李伟达
ZHU, Jinhui
朱晋辉
Title: WOUND DRESSING AND PREPARATION METHOD THEREFOR
Abstract:
Provided is a wound dressing formed by a silicone film layer and an electrospun nano-fibre layer. The preparation method for the wound dressing comprises firstly evenly mixing the silicone, liquid paraffin, n-hexane and Span-80, casting the mixed solution into a mould made of polytetrafluoroethylene by a film casting method, steeping the silicone film in ethanol after drying and film forming, removing the paraffin ingredient so as to obtain a silicone film with a porous structure; and then electrospinning one layer of biodegradable polymer nano-fibre on the silicone film by an electrostatic spinning method, and performing radiation sterilisation after drying to obtain the finished product. The wound dressing prepared by the method has good moisturising properties and air permeability, can moisturise the wound and prevent the formation of a hypertrophic scar; and the unique support effect of the nano-fibre layer thereof can improve the formation of body tissues and speed up wound healing.