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1. (WO2017144851) MEASUREMENT OF CARDIAC FIRST PHASE EJECTION FRACTION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/144851 International Application No.: PCT/GB2017/050290
Publication Date: 31.08.2017 International Filing Date: 06.02.2017
IPC:
A61B 5/021 (2006.01) ,A61B 8/14 (2006.01) ,A61B 5/026 (2006.01) ,A61B 5/029 (2006.01) ,A61B 5/055 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
02
Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
021
Measuring pressure in heart or blood vessels
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
8
Diagnosis using ultrasonic, sonic or infrasonic waves
13
Tomography
14
Echo-tomography
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
02
Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
026
Measuring blood flow
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
02
Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
026
Measuring blood flow
029
Measuring blood output from the heart, e.g. minute volume
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
05
Measuring for diagnosis by means of electric currents or magnetic fields
055
involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
Applicants:
GU, Haotian; GB
CHOWIENCZYK, Philip Jan; GB
Inventors:
GU, Haotian; GB
CHOWIENCZYK, Philip Jan; GB
Agent:
WALLIN, Nicholas; GB
Priority Data:
1603216.124.02.2016GB
Title (EN) MEASUREMENT OF CARDIAC FIRST PHASE EJECTION FRACTION
(FR) MESURE DE LA FRACTION D'ÉJECTION DE LA PREMIÈRE PHASE CARDIAQUE
Abstract:
(EN) Embodiments of the invention provide a method and system for measuring first phase ejection fraction where simultaneous measurement of the systolic pressure during systole of a subject is undertaken at the same time as measurement of the left ventricle volume (LVV). The pressure waveform is then analyzed, for example using automated signal processing techniques, to find a time T1 which corresponds to the point at which the rate of change of systolic pressure during systole begins to reduce. The left ventricle volume at this time T1 is then found from the previous measurements of LVV obtained at the same time as the systolic pressure measurement, and the first phase ejection fraction then calculated in dependence on the LVV at time T1 and the LVV at the start of systole i.e. the end diastolic volume (EDV). In particular embodiments, the first phase ejection fraction is the difference between LVV at EDV and LVV at time T1.
(FR) Des modes de réalisation de l'invention concernent un procédé et un système de mesure de la fraction d'éjection de la première phase où la mesure simultanée de la pression systolique pendant la systole d'un sujet est effectuée en même temps que la mesure du volume du ventricule gauche (LVV). La forme d'onde de pression est ensuite analysée, par exemple à l'aide de techniques de traitement de signaux automatisées, de manière à trouver un instant T1 qui correspond au point auquel le taux de variation de la pression systolique pendant la systole commence à diminuer. Le volume du ventricule gauche à cet instant T1 est ensuite déterminé à partir des mesures précédentes de LVV obtenues en même temps que la mesure de pression systolique, et la fraction d'éjection de la première phase est ensuite calculée en fonction du LVV à l'instant T1 et du LVV au début de la systole, c'est-à-dire du volume diastolique final (EDV). Selon des modes de réalisation particuliers, la fraction d'éjection de la première phase est la différence entre le LVV à l'EDV et le LVV à l'instant T1.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3419512US20190053717CN109414205