CLAIMS:
1. A method of treating PIK3CA-Related Overgrowth Spectrum (PROS) in a subject in need thereof comprising a step of administrating the subject with a therapeutically effective amount of BYL719.
2. The method of treating according to claim 1, wherein the PROS disorder is Congenital, Lipomatous, Overgrowth, Vascular Malformations, Epidermal Nevi and Spinal/Skeletal Anomalies and/or Scoliosis (CLOVES) syndrome.
3. The method of treating according to claim 1, wherein the PROS disorder is Klippel- Trenaunay syndrome.