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1. (WO2017139212) PARTICLE DELIVERY OF RAPAMYCIN TO THE LIVER
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/139212 International Application No.: PCT/US2017/016639
Publication Date: 17.08.2017 International Filing Date: 06.02.2017
IPC:
A61K 31/436 (2006.01) ,A61K 9/14 (2006.01) ,A61K 9/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
436
the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
Applicants:
CYTA THERAPEUTICS, INC. [US/US]; 110 Canal Street, 4th Floor Lowell, MA 01852, US
Inventors:
FARACI, W., Stephen; US
FENDROCK, Bernadette, C.; US
HERRERA, Roman; US
Agent:
HAYMAN, Mark, L.; US
LIN, Yi-chia; US
CURRIE, Matthew, T.; US
FRANK, Steven, J.; US
ALTIERI, Stephen; US
Priority Data:
62/292,39808.02.2016US
Title (EN) PARTICLE DELIVERY OF RAPAMYCIN TO THE LIVER
(FR) ADMINISTRATION DE PARTICULES DE RAPAMYCINE AU FOIE
Abstract:
(EN) The present invention provides liver-specific delivery of rapamycin or an analogue or derivative thereof using particle delivery systems. In some embodiments, the particle delivery systems provide sustained and/or controlled levels of rapamycin or an analogue or derivative thereof at the liver to induce desired biological effects.
(FR) La présente invention concerne l'administration spécifique au foie de rapamycine ou d'un analogue ou dérivé de celle-ci à l'aide de systèmes d'administration de particules. Dans certains modes de réalisation, les systèmes d'administration de particules fournissent au foie des niveaux à action prolongée et/ou contrôlée de rapamycine ou d'un analogue ou dérivé de celle-ci pour induire les effets biologiques recherchés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)