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1. (WO2017138007) MICROBIOME-BASED DIAGNOSIS, PREDICTION AND TREATMENT OF RELAPSING OBESITY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/138007 International Application No.: PCT/IL2017/050187
Publication Date: 17.08.2017 International Filing Date: 14.02.2017
Chapter 2 Demand Filed: 14.12.2017
IPC:
C12Q 1/68 (2006.01) ,A61K 35/741 (2015.01) ,A23L 33/135 (2016.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
[IPC code unknown for A61K 35/741][IPC code unknown for A23L 33/135]
Applicants:
YEDA RESEARCH AND DEVELOPMENT CO. LTD. [IL/IL]; at the Weizmann Institute of Science P.O. Box 95 7610002 Rehovot, IL
Inventors:
ELINAV, Eran; IL
SEGAL, Eran; IL
Agent:
EHRLICH, Gal; IL
Priority Data:
62/295,09414.02.2016US
62/423,29917.11.2016US
Title (EN) MICROBIOME-BASED DIAGNOSIS, PREDICTION AND TREATMENT OF RELAPSING OBESITY
(FR) DIAGNOSTIC BASÉ SUR LE MICROBIOME, PRÉDICTION ET TRAITEMENT DE L'OBÉSITÉ DE RECHUTE
Abstract:
(EN) A method of analyzing the likelihood of weight regain in a subject who has reached a target weight by practicing a weight loss program is disclosed. The method comprises determining an amount or presence of at least one microbe and/or product thereof in the gut microbiome of the subject, wherein the amount of the at least one microbe is altered during a prior weight gain period of the subject to reach a level representative of an obese subject and further wherein the amount of the at least one microbe is retained at the level following the weight loss program, wherein the amount or presence of the at least one microbe or product thereof is predictive of weight regain.
(FR) La présente invention concerne un procédé d'analyse de la probabilité d'une reprise de poids chez un sujet qui a atteint un poids cible en suivant un programme de perte de poids. Le procédé comprend la détermination d'une quantité ou de la présence d'au moins un microbe et/ou d'un produit de ce dernier dans le microbiome intestinal du sujet, la quantité dudit microbe étant modifiée durant une période antérieure de gain pondéral du sujet pour atteindre un niveau représentatif d'un sujet obèse et, en outre, la quantité dudit microbe étant maintenue au niveau suivant le programme de perte de poids, la quantité ou la présence dudit microbe ou de son produit permettant de prédire une reprise de poids.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3414346US20190142875