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1. (WO2017137900) AMORPHOUS LUMACAFTOR AND ITS SOLID DISPERSION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/137900 International Application No.: PCT/IB2017/050679
Publication Date: 17.08.2017 International Filing Date: 08.02.2017
IPC:
C07D 405/12 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
405
Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
Applicants:
LUPIN LIMITED [IN/IN]; Kalpataru Inspire, 3rd Floor, Off Western Express Highway, Santacruz (East), Maharashtra, Mumbai 400 055, IN
Inventors:
RAJPUT, Lalitkumar, Dilipsing; IN
BHOR, Malhari, Deoram; IN
JANGAM, Sonraj, Bholenath; IN
SHIVDAVKAR, Radhakrishna; IN
SHRIVASTAVA, Dhananjai; IN
SINGH, Girij, Pal; IN
VINCHURKAR, Arjun, Nishikant; IN
Agent:
MAJUMDAR, Subhatosh; IN
GANGULI, Sanchita; IN
SEN, Abhishek; IN
VENKATESH, Mythili; IN
MAJUMDAR, Amrita; IN
KUNDU, Subarna; IN
CHAUBEY, Priyanka; IN
Priority Data:
20162100478010.02.2016IN
20162101684513.05.2016IN
20162102937829.08.2016IN
Title (EN) AMORPHOUS LUMACAFTOR AND ITS SOLID DISPERSION
(FR) LUMACAFTOR AMORPHE ET SA DISPERSION SOLIDE
Abstract:
(EN) The present invention provides a novel amorphous form of lumacaftor and its preparation by various methods. The patent invention also relates to novel lumacaftor hydrobromide crystalline form A and process for its preparation. The present invention relates to amorphous lumacaftor premixed with an excipient and process for the preparation of the premix.
(FR) La présente invention concerne une nouvelle forme de lumacaftor amorphe et sa préparation par divers procédés. La présente invention concerne également une nouvelle forme A cristalline de bromhydrate lumacaftor et son procédé de préparation. La présente invention concerne du lumacaftor amorphe prémélangé avec un excipient et un procédé de préparation de ce prémélange.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)