Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2017137808) A METHOD OF MANUFACTURING A PHARMACEUTICAL ACTIVE PREPOLYMER FORMULATION, FORMULATIONS OBTAINED BY THE METHOD AND USES OF THE FORMULATION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/137808 International Application No.: PCT/IB2016/050752
Publication Date: 17.08.2017 International Filing Date: 12.02.2016
Chapter 2 Demand Filed: 12.09.2017
IPC:
A61L 15/26 (2006.01) ,A61L 15/42 (2006.01) ,A61L 15/44 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
15
Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
16
Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
22
containing macromolecular materials
26
Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
15
Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
16
Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
42
Use of materials characterised by their function or physical properties
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
15
Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
16
Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
42
Use of materials characterised by their function or physical properties
44
Medicaments
Applicants:
PHARMAPLAST SAE [EG/EG]; Amria Free Zone Alexandria, 23512, EG
HOLME NIELSEN, Marianne [DK/DK]; DK (BZ)
Inventors:
ATTEIA, Mamdouh; EG
AZIZ, Dina; EG
ZAKI, Mena; EG
ADEL, Mina; EG
GAD, Wassim; EG
Agent:
HOLME PATENT A/S; Valbygårdsvej 33 2500 Valby, DK
Priority Data:
Title (EN) A METHOD OF MANUFACTURING A PHARMACEUTICAL ACTIVE PREPOLYMER FORMULATION, FORMULATIONS OBTAINED BY THE METHOD AND USES OF THE FORMULATION
(FR) PROCÉDÉ DE FABRICATION D'UNE FORMULATION DE PRÉPOLYMÈRE ACTIF PHARMACEUTIQUE, FORMULATIONS OBTENUES PAR CE PROCÉDÉ ET UTILISATIONS DE LA FORMULATION
Abstract:
(EN) A method of manufacturing a pharmaceutical active prepolymer formulation includes the steps of combining in a reactor at least one polyol compound, at least one aromatic di-isocyanate compound, and/or at least one aliphatic di-isocyanate compound, and a pharmaceutical active agent having a water or moisture content of maximum 1.0 wt/wt%. Then the at least one polyol compound and/or the at least one di-isocyanate compound is allowed to prepolymerize to integrate the pharmaceutical active agent to obtain the pharmaceutical active prepolymer formulation. The pharmaceutical active prepolymer formulation can be made into a foam for use in pharmaceutical active wound dressings.
(FR) La présente invention concerne un procédé de fabrication d'une formulation de prépolymère actif pharmaceutique consistant à combiner dans un réacteur au moins un composé polyol, au moins un composé di-isocyanate aromatique et/ou au moins un composé di-isocyanate aliphatique, et un principe actif pharmaceutique comportant une teneur en eau ou en humidité d'au plus 1,0 % en poids/poids. Puis, le ou les composés polyols et/ou le ou les composés diisocyanate se prépolymérisent en vue d'intégrer le principe actif pharmaceutique en vue d'obtenir la formulation de prépolymère actif pharmaceutique. La formulation de prépolymère actif pharmaceutique peut être transformée en une mousse destinée à être utilisée dans des pansements actifs pharmaceutiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3413932