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1. (WO2017137616) FIXATIVE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/137616 International Application No.: PCT/EP2017/053089
Publication Date: 17.08.2017 International Filing Date: 10.02.2017
IPC:
G01N 1/30 (2006.01) ,A61K 45/06 (2006.01) ,A61K 31/496 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1
Sampling; Preparing specimens for investigation
28
Preparing specimens for investigation
30
Staining; Impregnating
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
496
Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
Applicants:
BIOSEPAR GESELLSCHAFT FÜR MEDIZIN- UND LABORTECHNIK MBH [DE/DE]; Adolf-Kolping-Str. 34 84359 Simbach am Inn, DE (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IR, IS, IT, JP, KE, KG, KH, KM, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW)
SZABADOS, Andreas [DE/DE]; DE (US)
Inventors:
SZABADOS, Andreas; DE
Agent:
VON BÜLOW & TAMADA; Rotbuchenstr. 6 81547 München, DE
Priority Data:
10 2016 102 346.910.02.2016DE
Title (DE) FIXATIVUM
(EN) FIXATIVE
(FR) FIXATIF
Abstract:
(DE) Die Erfindung betrifft ein Fixativum zur Konservierung von organischem Gewebe und Zellverbänden, umfassend ein hydrophiles Denaturierungsmittel zum strukturellen Verändern der Moleküle des organischen Gewebes, ein lipophobes Lösungsmittel, in dem das Denaturierungsmittel gelöst ist, und ein in dem Lösungsmittel gelöstes amphiphiles Infiltrationsmittel zum Lösen von Fetten an der Oberfläche des biologischen Gewebes, um ein Eindringen des Denaturierungsmittels in das biologische Gewebe zu beschleunigen.
(EN) The invention relates to a fixative for the preservation of organic tissue and cell aggregates, comprising a hydrophilic denaturant for structural change of the molecules of the organic tissue, a lipophobic solvent, in which said denaturant is dissolved, and an amphiphilic infiltration agent which is dissolved in the solvent for dissolving fats on the surface of the biological tissue in order to accelerate a penetration of the denaturant into the biological tissue.
(FR) La présente invention concerne un fixatif pour la conservation de tissus organiques et d’agrégations cellulaires, qui comporte un agent de dénaturation hydrophile destiné provoquer une modification structurale des molécules du tissu organique, un solvant lipophobe dans lequel l’agent dénaturant est dissous, et un agent d’infiltration amphiphile dissous dans le solvant, destiné à dissoudre les graisses situées à la surface du tissu biologique pour accélérer la pénétration de l’agent de dénaturation dans les tissus biologiques.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)
Also published as:
CA3013162EP3414547US20190033180