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1. (WO2017137570) METHOD TO EVALUATE THE STABILITY OF A PROTEIN-BASED FORMULATION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/137570 International Application No.: PCT/EP2017/053021
Publication Date: 17.08.2017 International Filing Date: 10.02.2017
IPC:
G01N 33/30 (2006.01) ,G01N 13/02 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
26
Oils; viscous liquids; paints; inks
28
Oils
30
for lubricating properties
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
13
Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
02
Investigating surface tension of liquids
Applicants:
BECTON DICKINSON FRANCE [FR/FR]; 11, Rue Aristide Bergès 38800 Le Pont de Claix, FR
Inventors:
CHEVOLLEAU, Tzvetelina; FR
HAMEL, Jean-Bernard; FR
Agent:
REGIMBEAU; REGIMBEAU 139, rue Vendôme 69477 LYON CEDEX 06, FR
Priority Data:
16305152.710.02.2016EP
Title (EN) METHOD TO EVALUATE THE STABILITY OF A PROTEIN-BASED FORMULATION
(FR) PROCÉDÉ POUR ÉVALUER LA STABILITÉ DE FORMULATION À BASE DE PROTÉINE
Abstract:
(EN) The invention relates to a method to evaluate the stability of a protein-based formulation comprising a protein, a peptide and/or a protein derivative and a buffer relative to a lubricant of a lubricated container in which said formulation is intended to be stored, comprising: a)Evaluating a decrease over time of interfacial tension between the buffer and the lubricant, b)Evaluating a decrease over time of interfacial tension between the protein-based formulation and the lubricant, c)Identifying at least one component of the protein-based formulation interacting with the lubricant by comparing the decrease evaluated instep b)with the decrease evaluated in step a).
(FR) L'invention concerne un procédé pour évaluer la stabilité d'une formulation à base de protéine comprenant une protéine, un peptide et/ou un dérivé de protéine et un tampon par rapport à un lubrifiant d'un récipient lubrifié dans lequel ladite formulation est destinée à être stockée, consistant : a) à évaluer une diminution au fil du temps d'une tension interfaciale entre le tampon et le lubrifiant, b) à évaluer une diminution au fil du temps d'une tension interfaciale entre la formulation à base de protéine et le lubrifiant, c) à identifier au moins un constituant de la formulation à base de protéine interagissant avec le lubrifiant en comparant la diminution évaluée dans l'étape b) avec la diminution évaluée dans l'étape a).
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
IN201817030343EP3414568US20190064138