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1. (WO2017137427) DETECTION OF CANCER OF THE ESOPHAGUS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/137427 International Application No.: PCT/EP2017/052730
Publication Date: 17.08.2017 International Filing Date: 08.02.2017
IPC:
C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
UCL BUSINESS PLC [GB/GB]; The Network Building 2nd Floor 97 Tottenham Court Road London W1T 4TP, GB
Inventors:
LOVAT, Laurence; GB
GRAHAM, David George; GB
HAMOUDI, Rifat; GB
ROSENFELD, Avi; IL
KHAN, Saif U Rehman; GB
Agent:
KREMER, Simon; GB
ADDISS, John; GB
ANDREWS, Robert; GB
BAILEY, Sam; GB
BRASNETT, Adrian; GB
BREARLEY, Sarah; GB
CARLISLE, Julie; GB
CARTER, Stephen; GB
CASLEY, Christopher; GB
CLEGG, Richard; GB
CRIPPS, Joanna; GB
DALE, Elizabeth; GB
DENISON, Christopher; GB
DUNNE, Paul; GB
FORREST, Graham; GB
GILL, Stephen; GB
GRAHAM, Emma; GB
GREEN, Katherine; GB
GREGORY, Adam; GB
HACKNEY, Nigel; GB
HARRISON, Susan; GB
HAYES, Emily; GB
HODSDON, Stephen; GB
JOHNSON, Richard; GB
JONES, Rachel; GB
KEIRSTEAD, Tanis; GB
KIDDLE, Simon; GB
LEACH, James; GB
LENTHALL, Joseph; GB
LYONS, June; GB
MCGUINN, Callum; GB
MOORE, Graeme; GB
NAYLOR, Matthew; GB
NICHOLLS, Kathryn; GB
OXLEY, Rachel; GB
PARRY, Simon; GB
SALISBURY, Frances; GB
SMITH, Matthew; GB
STONER, Patrick; GB
SUTCLIFFE, Nicholas; GB
TOLLERVEY, Rebecca; GB
WALTON, Seán; GB
WARD, Eliot; GB
WATSON, Robert; GB
WEBSTER, Jeremy; GB
WESCOTT, Rhiannon; GB
WILLS, Jonathan; GB
WOOLLEY, Lindsey; GB
WYTENBURG, Wilhelmus; GB
Priority Data:
1602210.508.02.2016GB
Title (EN) DETECTION OF CANCER OF THE ESOPHAGUS
(FR) DÉTECTION DU CANCER DE L’ŒSOPHAGE
Abstract:
(EN) The invention provides identification system for ascertaining who is at risk of having or already has high-risk pre-malignant or malignant lesions of their oesophagus / gastro-oesophageal junction. The system is based upon transcriptomic expression data from RNA extracted from saliva samples as well as optionally demographic, risk factor and symptom data. Also provided are related materials and methods, including such as primers and kits.
(FR) L'invention concerne un système d'identification permettant de déterminer, chez un patient, le risque ou le risque élevé de présenter des lésions prémalignes ou malignes de l’œsophage/du cardia. Ce système est fondé sur des données d'expression transcriptomiques d'ARN provenant d'échantillons de salive, et éventuellement des données démographiques, les facteurs de risque et des données relatives aux symptôme. L'invention concerne également des matériaux et des procédés associés comprenant, par exemple, des amorces et des kits.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)