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1. WO2017137252 - AN AEROSOL GENERATOR

Publication Number WO/2017/137252
Publication Date 17.08.2017
International Application No. PCT/EP2017/051453
International Filing Date 25.01.2017
IPC
A61M 11/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
11Sprayers or atomisers specially adapted for therapeutic purposes
A61M 15/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
15Inhalators
B05B 17/00 2006.1
BPERFORMING OPERATIONS; TRANSPORTING
05SPRAYING OR ATOMISING IN GENERAL; APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL
BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
17Apparatus for spraying or atomising liquids or other fluent materials, not covered by any other group of this subclass
CPC
A61M 11/005
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
11Sprayers or atomisers specially adapted for therapeutic purposes
005using ultrasonics
A61M 15/0085
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
15Inhalators
0085using ultrasonics
B05B 17/0638
BPERFORMING OPERATIONS; TRANSPORTING
05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
17Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
04operating with special methods
06using ultrasonic ; or other kinds of; vibrations
0607generated by electrical means, e.g. piezoelectric transducers
0638spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
B05B 17/0646
BPERFORMING OPERATIONS; TRANSPORTING
05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
17Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
04operating with special methods
06using ultrasonic ; or other kinds of; vibrations
0607generated by electrical means, e.g. piezoelectric transducers
0638spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
0646Vibrating plates, i.e. plates being directly subjected to the vibrations, e.g. having a piezoelectric transducer attached thereto
B05B 17/0653
BPERFORMING OPERATIONS; TRANSPORTING
05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
17Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
04operating with special methods
06using ultrasonic ; or other kinds of; vibrations
0607generated by electrical means, e.g. piezoelectric transducers
0653Details
Applicants
  • KONINKLIJKE PHILIPS N.V. [NL]/[NL]
Inventors
  • HIJLKEMA, Markus
Agents
  • KRUK, Arno
  • DE HAAN, Poul, Erik
Priority Data
16154653.608.02.2016EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) AN AEROSOL GENERATOR
(FR) GÉNÉRATEUR D'AÉROSOL
Abstract
(EN) Nebulizers are used to deliver a medicine to a patient's lungs in the form of an airstream, with fluid comprising the medicine entrained in the airstream. To enable the fluid to be entrained in the airstream, a nebulizer contains an aerosol generator typically comprising a vibratory element (28) with a piezoelectric actuator. There is a need to frequently sterilize the nebulizer. This involves dipping the nebulizer in boiling water for a significant time. It has been found that repeated sterilization cycles can force water through gaps in the vibratory element, and its encapsulation (26), and damage the piezo element. The present invention proposes to more effectively seal the piezo of the vibratory element (28) from the effects of water ingress. In particular, it is proposed to create, at an interface of the vibratory element (28) and the encapsulating element (26), a discontinuity which provides a barrier geometry. Through capillary forces, the progress of water towards the piezoelectric element (12) comprised in the vibratory element (28) is arrested, and the lifetime of the aerosol generator is improved.
(FR) La présente invention concerne des nébuliseurs utilisés pour délivrer un médicament aux poumons d'un patient sous la forme d'un flux d'air, un liquide comprenant le médicament étant entraîné dans le flux d'air. Pour permettre au liquide d'être entraîné dans le flux d'air, un nébuliseur contient un générateur d'aérosol comprenant généralement un élément vibrant (28) doté d'un actionneur piézoélectrique. Il est nécessaire de stériliser fréquemment le nébuliseur. À cette fin, le nébuliseur est plongé dans de l'eau bouillante pendant une durée importante. Il a été constaté que les cycles de stérilisation répétés peuvent provoquer une pénétration d'eau dans l'élément vibrant et dans son encapsulation (26) à travers des interstices, et endommager l'élément piézoélectrique. La présente invention propose la réalisation d'une étanchéité plus efficace de l'élément piézoélectrique de l'élément vibrant (28) contre les effets de l'infiltration d'eau. En particulier, il est proposé de créer, au niveau d'une interface de l'élément vibrant (28) et l'élément d'encapsulation (26), une discontinuité qui présente une géométrie de barrière. La progression de l'eau vers l'élément piézoélectrique (12) inclus dans l'élément vibrant (28) est interrompue par des forces capillaires, et la durée de vie du générateur d'aérosol est augmentée.
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