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1. WO2017136950 - DECELLULARISED CELL WALL STRUCTURES FROM PLANTS AND FUNGUS AND USE THEREOF AS SCAFFOLD MATERIALS

Publication Number WO/2017/136950
Publication Date 17.08.2017
International Application No. PCT/CA2017/050163
International Filing Date 10.02.2017
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
36
containing ingredients of undetermined constitution or reaction products thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
46
Ingredients of undetermined constitution or reaction products thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
96
containing materials, or derivatives thereof, of undetermined constitution
97
of vegetable origin, e.g. plant extracts
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A61L 27/36 (2006.01)
A61K 47/46 (2006.01)
A61K 8/97 (2017.01)
A61K 9/00 (2006.01)
CPC
A61L 2300/414
A61L 2430/02
A61L 2430/16
A61L 2430/32
A61L 2430/40
A61L 27/3637
Applicants
  • UNIVERSITY OF OTTAWA [CA/CA]; Innovation Support Services 800 King Edward Avenue Room 3042 Ottawa, Ontario K1N 6N5, CA
Inventors
  • PELLING, Andrew Edward; CA
  • CUERRIER, Charles Michel; CA
  • MODULEVSKY, Daniel J.; CA
  • HICKEY, Ryan Joseph; CA
Agents
  • NEWTON, Trevor; CA
  • BAKER, James D.; CA
  • BOWN, Christopher D.; CA
  • HARRIS, John D.; CA
  • LEDWELL, M. Kent; CA
  • ROY, Matthew; CA
  • SCHROEDER, Hans; CA
  • SPRIGINGS, Mark; CA
  • WILKIE, Jennifer; CA
Priority Data
62/294,67112.02.2016US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DECELLULARISED CELL WALL STRUCTURES FROM PLANTS AND FUNGUS AND USE THEREOF AS SCAFFOLD MATERIALS
(FR) STRUCTURES DE PAROIS CELLULAIRES DÉCELLULARISÉES PROVENANT DE PLANTES ET DE CHAMPIGNONS ET LEUR UTILISATION COMME MATÉRIAUX D'ÉCHAFAUDAGE
Abstract
(EN)
Provided herein are scaffold biomaterials comprising a decellularised plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularised plant or fungal tissue comprising a cellulose- or chitin-based 3-dimensional porous structure. Methods for preparing such scaffold biomaterials, as well as uses thereof as an implantable scaffold for supporting animal cell growth, for promoting tissue regeneration, for promoting angiogenesis, for a tissue replacement procedure, and/or as a structural implant for cosmetic surgery are also provided. Therapeutic treatment and/or cosmetic methods employing such scaffolds are additionally described.
(FR)
L'invention concerne des biomatériaux d'échafaudage comprenant un tissu végétal ou fongique décellularisé à partir duquel sont éliminés les matériaux cellulaires et les acides nucléiques du tissu, ledit tissu végétal ou fongique décellularisé comprenant une structure poreuse tridimensionnelle à base de cellulose ou de chitine. L'invention concerne également des procédés de préparation de tels biomatériaux d'échafaudage, ainsi que leurs utilisations comme échafaudage implantable pour supporter la croissance de cellules animales, pour favoriser la régénération tissulaire, pour favoriser l'angiogenèse, pour une procédure de remplacement des tissus, et/ou comme implant structural pour une chirurgie esthétique. L'invention concerne en outre des procédés cosmétiques et/ou de traitement thérapeutique utilisant de tels échafaudages.
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