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1. (WO2017136892) METHOD OF DIAGNOSIS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/136892 International Application No.: PCT/AU2017/050111
Publication Date: 17.08.2017 International Filing Date: 10.02.2017
IPC:
G01N 33/50 (2006.01) ,C12Q 1/68 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
LA TROBE UNIVERSITY [AU/AU]; Innovation and Commercialisation Suite 4, TEC Building 2 Bundoora, Victoria 3086, AU
Inventors:
PARKER, Belinda Sheree; AU
DUIVENVOORDEN, Hendrika Martha; AU
Agent:
WATERMARK INTELLECTUAL PROPERTY PTY LTD; Level 1, 109 Burwood Road Hawthorn, Victoria 3122, AU
Priority Data:
201690047211.02.2016AU
Title (EN) METHOD OF DIAGNOSIS
(FR) PROCÉDÉ DE DIAGNOSTIC
Abstract:
(EN) The present invention relates generally to a method of detecting a risk of the progression of a pre-invasive neoplasia of the glandular epithelium. More particularly, the present invention provides a method of detecting a risk of the progression from a pre-invasive breast neoplasia by screening for the level of expression of Stefin A in the myoepithelial cells. The method of the present invention is useful in a range of applications including, but not limited to, assessing a neoplastic condition, monitoring the progression of such a condition, predicting the likelihood of a subject progressing to a more advance disease state or informing decisions in relation to the design of treatment schedules.
(FR) La présente invention concerne de manière générale un procédé de détection d'un risque de progression d'une néoplasie pré-invasive de l'épithélium glandulaire. Plus particulièrement, la présente invention concerne un procédé de détection d'un risque de progression d'une néoplasie du sein pré-invasive en déterminant le niveau d'expression de la Stéfine A dans les cellules myoépithéliales. Le procédé de la présente invention est utile dans une gamme d'applications comprenant, mais sans y être limité, l'évaluation d'un état néoplasique, la surveillance de la progression d'un tel état, la prévision de la probabilité que l'état d'un sujet évoluera vers un état de maladie plus avancé ou la semonce de décisions se rapportant à la conception de programmes de traitement.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU2017217248US20190033314