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1. (WO2017136745) ORAL DOSAGE FORM WITH DRYING AGENT FOR DELIVERY OF ACTIVE AGENT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/136745 International Application No.: PCT/US2017/016539
Publication Date: 10.08.2017 International Filing Date: 03.02.2017
IPC:
A61K 9/20 (2006.01) ,A61K 38/31 (2006.01) ,A61K 9/28 (2006.01) ,A61K 9/50 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
31
Somatostatins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
28
Dragees; Coated pills or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
Applicants:
ENTREGA INC. [US/US]; 500 Boylston Street Boston, Massachusetts 02116, US
Inventors:
BONNER, Daniel; US
JANTZ, John; US
TRAN, Peter; US
SHAPIRO, Rachel; US
PILLA, Nicholas; US
JACOB, Jules; US
KUO, Braden; US
GARDNER, Colin Robert; US
SHIVANAND, Padmaja; US
BARLOW, Jacob; US
FERREIRA, Lisa Viana; US
Agent:
COTTON, Abigail; US
Priority Data:
62/291,81205.02.2016US
62/382,36201.09.2016US
Title (EN) ORAL DOSAGE FORM WITH DRYING AGENT FOR DELIVERY OF ACTIVE AGENT
(FR) FORME GALÉNIQUE ORALE COMPRENANT UN AGENT DESSICCATIF POUR L'ADMINISTRATION D'UN AGENT ACTIF
Abstract:
(EN) A pharmaceutically acceptable oral dosage form for delivery of an agent to an intestinal site has one or more active agent regions having an active agent to be delivered to the intestinal site, one or more drying agent regions having at least one drying agent therein capable of drying an area about the intestinal site, the one or more drying agent regions being separate from the one or more active agent regions, and a protective coating at least partially covering a surface of the form. The dosage form has a fluid uptake capacity as measured for the entire dosage form when immersed in a fluid media according to a Dosage Form Fluid Uptake Assay of at least about 20 g fluid per dosage form.
(FR) La présente invention concerne une forme galénique orale pharmaceutiquement acceptable pour l'administration d'un agent à un site intestinal qui comprend une ou plusieurs régions d'agent actif comprenant un agent actif à administrer au site intestinal, une ou plusieurs régions d'agent dessiccatif comprenant au moins un agent dessiccatif en leur sein permettant de sécher une zone entourant le site intestinal, ladite ou lesdites régions d'agent dessiccatif étant séparées de ladite ou desdites régions d'agent actif, et un enrobage protecteur recouvrant au moins en partie une surface de la forme. La forme galénique présente une capacité d'absorption de fluide, telle que mesurée pour la forme galénique entière lorsqu'elle est immergée dans un milieu fluide selon un dosage d'absorption de fluide d'une forme galénique, d'au moins environ 20 g de fluide par forme galénique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CA3012698EP3411019