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1. (WO2017136562) BISPECIFIC BINDING PROTEINS FOR PD-L1 AND KDR
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/136562 International Application No.: PCT/US2017/016230
Publication Date: 10.08.2017 International Filing Date: 02.02.2017
IPC:
A61K 39/395 (2006.01) ,C07K 16/22 (2006.01) ,C07K 16/28 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
22
against growth factors
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
Applicants:
KADMON CORPORATION, LLC [US/US]; 450 East 29th Street New York, NY 10016, US
Inventors:
ZHU, Zhenping; US
LU, Dan; US
Agent:
SOMERVILLE, Deborah, A.; US
SHEPPARD, Peter, A.; US
BARRISON, Flynn; US
MA, Kenneth; US
GLYNN, Christopher, W.; US
Priority Data:
62/290,35002.02.2016US
Title (EN) BISPECIFIC BINDING PROTEINS FOR PD-L1 AND KDR
(FR) PROTÉINES DE LIAISON BISPÉCIFIQUES POUR PD-L1 ET KDR
Abstract:
(EN) Provided are bispecific binding proteins such as bispecific antibodies that bind to both human PD-L1 and human KDR. The bispecific binding proteins are useful for treating diseases and conditions characterized by immunosuppression and/or excessive angiogenesis.
(FR) L'invention concerne des protéines de liaison bispécifiques tels que des anticorps bispécifiques qui se lient à la fois au PD-L1 humain et au KDR humain. Les protéines de liaison bispécifiques sont utiles pour le traitement de maladies et d'états caractérisés par l'immunosuppression et/ou une angiogenèse excessive.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3411068CN109310755EA201891732