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1. (WO2017136519) ANTIMICROBIAL COMPOSITIONS FROM PRUNUS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/136519 International Application No.: PCT/US2017/016167
Publication Date: 10.08.2017 International Filing Date: 02.02.2017
IPC:
A61K 36/736 (2006.01) ,A01N 65/34 (2009.01) ,A61K 36/73 (2006.01) ,A61P 17/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
73
Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
736
Prunus, e.g. plum, cherry, peach, apricot or almond
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
65
Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
08
Magnoliopsida [dicotyledons]
34
Rosaceae [Rose family], e.g. strawberry, hawthorn, plum, cherry, peach, apricot or almond
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
73
Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17
Drugs for dermatological disorders
Applicants:
BRANCH RESEARCH LLC [US/US]; 14800 Conference Center Drive Suite 300 Chantilly, VA 20132, US
Inventors:
ROBERT, Donald; US
Agent:
WHITHAM, Michel E.; US
WHITHAM, Michael, E.; US
BRYCE, Miller, T.; US
CURTIS, Marshall, M.; US
Priority Data:
62/291,55505.02.2016US
Title (EN) ANTIMICROBIAL COMPOSITIONS FROM PRUNUS
(FR) COMPOSITIONS ANTIMICROBIENNES ISSUES DE PRUNUS
Abstract:
(EN) The foliage and stems of plant species from the family Rosacea, genus Prunus, yield natural pesticides when macerated. Hydrodistillation of macerated plant biomass yields a concentrated solution of organic volatile compounds that act synergistically as a natural pesticide, and as provided herein, also act synergistically as antimicrobial compounds. Volatile compounds liberated from Prunus biomass include 2-propanol, hexanal, trans-2-hexenal, 1 - hexanol, cis-3-hexenol, mandelonitrile, benzoic acid, benzaldehyde, benzyl alcohol, hydrocyanic acid and others. These compounds may be removed from the distillate and reformulated to form a standard concentrated solution, with benzaldehyde, mandelonitrile and hydrogen cyanide being the major components. Provided herein are methods of using these pesticides as a broad- spectrum bactericide. Components of the extract may act alone or synergistically to control both gram positive and gram negative genera of bacteria.
(FR) La présente invention concerne le feuillage et les tiges d'espèces végétales issues de la famille Rosacea, genre Prunus, produisant des pesticides naturels lorsqu'ils sont macérés. L'hydrodistillation d'une biomasse végétale macérée permet de produire une solution concentrée de composés organiques volatils qui agissent de façon synergique en tant que pesticide naturel, et selon l'invention, agissent également de façon synergique en tant que composés antimicrobiens. Les composés volatils libérés à partir de la biomasse de Prunus comprennent du 2-propanol, de l'hexanal, du trans-2-hexénal, du 1-hexanol, du cis-3-hexénol, du mandélonitrile, de l'acide benzoïque, du benzaldéhyde, de l'alcool benzylique, de l'acide cyanhydrique et autres. Ces composés peuvent être éliminés du distillat et reformulés en vue de former une solution concentrée standard, comportant comme constituants majeurs du benzaldéhyde, du mandélonitrile et du cyanure d'hydrogène. L'invention concerne des procédés d'utilisation de ces pesticides comme bactéricide à large spectre. Les constituants de l'extrait peuvent agir seuls ou de manière synergique en vue de lutter à la fois contre des bactéries des genres gram positif et gram négatif.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU2017215312CA3013715EP3411054