Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2017135739) ORAL COMPOSITE FORMULATION COMPRISING FAT-SOLUBLE DRUG AND SOLID PREPARATION COATED WITH OIL REPELLENT BASE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/135739 International Application No.: PCT/KR2017/001200
Publication Date: 10.08.2017 International Filing Date: 03.02.2017
IPC:
A61K 9/48 (2006.01) ,A61K 9/50 (2006.01) ,A61K 9/00 (2006.01) ,A61K 9/28 (2006.01) ,A61K 9/20 (2006.01) ,A61K 31/202 (2006.01) ,A61K 31/40 (2006.01) ,A61K 31/505 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
28
Dragees; Coated pills or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
20
having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
202
having three or more double bonds, e.g. linolenic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Applicants:
한국유나이티드제약 주식회사 KOREA UNITED PHARM. INC. [KR/KR]; 세종시 전동면 노장공단길 25-23 25-23, Nojanggongdan-gil, Jeondong-myeon, Sejong 30011, KR
사단법인 유나이티드사이언스알앤디센터 UNITED SCIENCE R&D CENTER [KR/KR]; 세종시 연기면 공단로 64 64, Gongdan-ro, Yeongi-myeon, Sejong 30058, KR
Inventors:
최연웅 CHOI, Yun Woong; KR
하대철 HA, Dae Chul; KR
권인호 KWON, In Ho; KR
김병진 KIM, Byung Jin; KR
송희용 SONG, Hee Yong; KR
권민석 KWON, Min-Seok; KR
민병구 MIN, Byung Gu; KR
조상민 CHO, Sang Min; KR
장재상 JANG, Jae Sang; KR
Agent:
손민 SON, Min; KR
Priority Data:
10-2016-001530605.02.2016KR
Title (EN) ORAL COMPOSITE FORMULATION COMPRISING FAT-SOLUBLE DRUG AND SOLID PREPARATION COATED WITH OIL REPELLENT BASE
(FR) FORMULATION COMPOSITE ORALE COMPRENANT UN MÉDICAMENT LIPOSOLUBLE ET PRÉPARATION SOLIDE ENROBÉE AVEC UNE BASE OLÉOFUGE
(KO) 지용성 약물 및 방유성 기제가 코팅된 고형제제를 포함하는 경구용 복합제제
Abstract:
(EN) The present invention relates to an oral composite formulation comprising: a capsule containing a first drug with fat solubility; and a solid preparation containing a second drug, the solid preparation being inserted inside the capsule and including an oil repellent base coating layer on a surface thereof. The oral composite formulation of the present invention, which comprises a capsule containing a first drug with fat solubility and a solid preparation inserted inside the capsule, the solid preparation including an oil repellent base coating layer on a surface thereof and containing a second drug, allows a simultaneous administration of two types of ingredient drugs, and here, the oil repellent base coating layer on the surface can prevent an active ingredient of the solid preparation from being released by the first drug with fat solubility and causing side reactions with the first drug with fat solubility, thereby delivering two types of active ingredients independently to desired sites without loss of the active ingredients, respectively.
(FR) La présente invention concerne une formulation composite orale comprenant : une capsule contenant un premier médicament liposoluble; et une préparation solide contenant un deuxième médicament, la préparation solide étant insérée à l'intérieur de la capsule comprenant une couche d'enrobage de base oléofuge sur une surface de celle-ci. La formulation composite orale de la présente invention, qui comprend une capsule contenant un premier médicament liposoluble et une préparation solide insérée à l'intérieur de la capsule, la préparation solide comprenant une couche de revêtement de base oléofuge sur une surface de celle-ci et contenant un deuxième médicament, permet une administration simultanée de deux types de médicaments composants et, dans la présente invention, la couche de revêtement de base oléfuge sur la surface peut éviter qu'une substance active de préparation solide soit libérée par le premier médicament liposoluble et cause des réactions secondaires avec le premier médicament liposoluble, de façon à administrer deux types de substances actives indépendamment à des sites souhaités sans perte des substances actives respectives.
(KO) 본 발명은 지용성 제1약물 함유 캡슐제; 및 상기 캡슐제 내부에 함입되어 있고, 표면에 방유성 기제 코팅층을 포함하는, 제2약물을 함유하는 고형제제를 포함하는 경구용 복합제제에 관한 것이다. 본 발명의 지용성 제1약물 함유 캡슐제에 상기 캡슐제 내부에 표면에 방유성 기제 코팅층을 포함하는, 제2약물을 함유하는 고형제제를 함입시킨 경구용 복합제제는 2종 성분의 약물을 동시에 투여할 수 있고, 이때 표면에 방유성 기제 코팅층으로 인해 고형제제의 유효성분이 지용성 제1약물에 의해 용출되거나 지용성 제1약물과 부반응을 일으키는 것을 차단할 수 있으므로, 유효성분의 손실 없이 원하는 부위에 독립적으로 2종의 유효성분을 각각 전달할 수 있다.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)
Also published as:
EP3412280US20190083409