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1. (WO2017135627) CARVEDILOL IMMEDIATE RELEASE FORMULATION HAVING IMPROVED MADESCENT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/135627 International Application No.: PCT/KR2017/000811
Publication Date: 10.08.2017 International Filing Date: 24.01.2017
IPC:
A61K 9/28 (2006.01) ,A61K 31/403 (2006.01) ,A61K 47/44 (2017.01) ,A61K 9/48 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
28
Dragees; Coated pills or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403
condensed with carbocyclic rings, e.g. carbazole
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
44
Oils, fats or waxes according to more than one of groups A61K47/02-A61K47/42109
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
Applicants:
SAMJIN PHARMACEUTICAL CO., LTD. [KR/KR]; 121, Wausan-ro Mapo-gu Seoul 04054, KR
Inventors:
CHO, Eui Hwan; KR
CHOI, Sung-Ju; KR
LEE, Sung-Woo; KR
SHIN, Hee-Jong; KR
KI, Min-Hyo; KR
CHOI, Mee-Hwa; KR
OH, Tae-Hoon; KR
Agent:
AHN, So Young; KR
Priority Data:
10-2016-001517705.02.2016KR
Title (EN) CARVEDILOL IMMEDIATE RELEASE FORMULATION HAVING IMPROVED MADESCENT
(FR) FORMULATION À LIBÉRATION IMMÉDIATE DE CARVÉDILOL PRÉSENTANT UNE MEILLEURE RÉACTION FACE À L’HUMIDITÉ
Abstract:
(EN) Disclosed is an immediate-release carvedilol formulation, which is configured such that a coating layer including a polymer, wax, fatty acid and/or fatty acid ester is formed on the surface thereof. This formulation has improved madescent, and thus can exhibit high stability, in which the initial appearance of the formulation can be maintained without cracking or breaking even under storage conditions at high relative humidity.
(FR) L'invention concerne une formulation de carvédilol à libération immédiate, qui est conçue de telle sorte qu'une couche de revêtement comprenant un polymère, une cire, un acide gras et/ou un ester d'acide gras est formée sur sa surface. Cette formulation est dotée d’une meilleure réaction face à l’humidité, et peut ainsi présenter une stabilité élevée, l’aspect initial de la formulation pouvant être conservé sans fissuration ou rupture, même dans des conditions de stockage à humidité relative élevée.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CN108601742EP3411020US20190038564