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1. (WO2017134466) INTRAMOLECULAR TRANS-SIALIDASE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/134466 International Application No.: PCT/GB2017/050291
Publication Date: 10.08.2017 International Filing Date: 06.02.2017
IPC:
A61K 31/7012 (2006.01) ,A61K 47/26 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7012
Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
26
Carbohydrates
Applicants:
QUADRAM INSTITUTE BIOSCIENCE [GB/GB]; Norwich Research Park Colney Lane Norwich NR4 7UA, GB
Inventors:
JUGE, Nathalie; GB
MONESTIER, Marie Maguelonne; GB
FIELD, Robert Andrew; GB
Agent:
BAILEY WALSH & CO LLP; P. Stephenson 1 York Place Leeds LS1 2DR, GB
Priority Data:
1602105.705.02.2016GB
Title (EN) INTRAMOLECULAR TRANS-SIALIDASE
(FR) TRANS-SIALIDASE INTRAMOLÉCULAIRE
Abstract:
(EN) The present invention relates to an intramolecular frans-sialidase (IT-sialidase) enzyme from Ruminococcus gnavus and fragments thereof. It also relates to methods of production of the IT- sialidase or its fragments, in addition to uses of the IT-sialidase, its fragments, or compositions comprising the IT-sialidase. One of the uses of the IT-sialidase or its fragments encompassed by the present invention is a method for production of 2,7-anhydro sialic acid derivatives. Further uses of the IT-sialidase enzyme include the therapeutic and prophylactic treatment of infections and respiratory conditions.
(FR) La présente invention concerne une enzyme trans-sialidase (IT-sialidase) intramoléculaire de Ruminococcus gnavus et ses fragments. L'invention concerne également des procédés de production de l'IT-sialidase ou de ses fragments, ainsi que des utilisations de l'IT-sialidase, de ses fragments, ou de compositions comprenant l'IT-sialidase. Une des utilisations de l'IT-sialidase ou de ses fragments couverte par la présente invention est un procédé de production de dérivés de l'acide 2,7-anhydro-sialique. D'autres utilisations de l'enzyme IT-sialidase comprennent le traitement thérapeutique et prophylactique d'infections et d'affections respiratoires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3411042US20190037899