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1. (WO2017132945) DESIGN AND APPLICATION OF MIRANCER MOLECULE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/132945 International Application No.: PCT/CN2016/073517
Publication Date: 10.08.2017 International Filing Date: 04.02.2016
IPC:
C12N 15/113 (2010.01) ,C12N 15/63 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
113
Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
Applicants:
中国科学技术大学 UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA [CN/CN]; 中国安徽省合肥市 包河区金寨路96号 96, Jinzhai Road, Baohe District Hefei, Anhui 230026, CN
Inventors:
朱涛 ZHU, Tao; CN
李高朋 LI, Gaopeng; CN
洛比E·彼得 LOBIE, E. Peter; SG
Agent:
中科专利商标代理有限责任公司 CHINA SCIENCE PATENT & TRADEMARK AGENT LTD.; 中国北京市 海淀区西三环北路87号4-1105室 Suite 4-1105, No. 87, West 3rd Ring North Rd., Haidian District Beijing 100089, CN
Priority Data:
Title (EN) DESIGN AND APPLICATION OF MIRANCER MOLECULE
(FR) CONCEPTION ET APPLICATION DE MOLÉCULE DE PROMOTEUR DE MICROARN ARTIFICIEL
(ZH) miRancer分子的设计与应用
Abstract:
(EN) Provided is a single-stranded RNA sequence for binding to a target microRNA. The single-stranded RNA sequence includes a 5'-end arm and a 3'-end arm. The 5'-end arm can bind, through complementary base pairing, with the target microRNA, and the 3'-end arm can bind, through complementary base pairing, with the 5'-end arm.
(FR) L'invention concerne une séquence d'ARN monocaténaire destinée à se lier à un microARN cible. La séquence d'ARN monocaténaire comprend un bras d'extrémité 5' et un bras d'extrémité 3'. Le bras d'extrémité 5' peut se lier, par appariement de bases complémentaires, au microARN cible, et le bras d'extrémité 3' peut se lier, par appariement de bases complémentaires, au bras d'extrémité 5'.
(ZH) 提供一种结合目标microRNA的单链RNA序列,该单链RNA序列具有5'端臂和3'端臂,所述5'端臂通过碱基互补配对与目标microRNA结合,所述3'端臂通过碱基互补配对与所述5'端臂结合。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)