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1. (WO2017132483) FREE-SOLUTION RESPONSE FUNCTION INTERFEROMETRY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/132483 International Application No.: PCT/US2017/015296
Publication Date: 03.08.2017 International Filing Date: 27.01.2017
IPC:
G01N 21/45 (2006.01) ,G01N 21/47 (2006.01) ,G01N 21/53 (2006.01) ,G01N 21/41 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
17
Systems in which incident light is modified in accordance with the properties of the material investigated
41
Refractivity; Phase-affecting properties, e.g. optical path length
45
using interferometric methods; using Schlieren methods
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
17
Systems in which incident light is modified in accordance with the properties of the material investigated
47
Scattering, i.e. diffuse reflection
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
17
Systems in which incident light is modified in accordance with the properties of the material investigated
47
Scattering, i.e. diffuse reflection
49
within a body or fluid
53
within a flowing fluid, e.g. smoke
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
17
Systems in which incident light is modified in accordance with the properties of the material investigated
41
Refractivity; Phase-affecting properties, e.g. optical path length
Applicants:
VANDERBILT UNIVERSITY [US/US]; 305 Kirkland Hall 2201 West End Avenue Nashville, Tennessee 37240, US
Inventors:
BORNHOP, Darryl J.; US
KUSSROW, Amanda; US
KAMMER, Michael; US
Agent:
SHORTELL, D. Brian; US
CHOI, Wendy A.; US
KATZ, Mitchell A.; US
LEVITIN, Galit; US
MARTY, Scott; US
JARVHOLM, Jonas E.; US
BROWN, Charley B.; US
ANDERSON, Joseph P. III; US
ZIMMERMAN, Sommer S.; US
MEADOWS, Brian C.; US
HATHCOCK, Kevin W.; US
MILLER, Richard W.; US
BASTUBA, Kevin T.; US
HOLDER, Sean; US
KLIEM, Michele A.; US
SCIASCIA-ZIRGER, Sandra; US
SZE, James; US
HOLLIS, Gaylon; US
TALCOTT, Jonathan A.; US
SEGAL, Marc S.; US
CHIONCHIO, John A.; US
Priority Data:
62/288,92629.01.2016US
Title (EN) FREE-SOLUTION RESPONSE FUNCTION INTERFEROMETRY
(FR) INTERFÉROMÉTRIE À FONCTION DE RÉPONSE EN SOLUTION LIBRE
Abstract:
(EN) Disclosed are methods for the free solution measurement of molecular interactions by refractive index sensing other than backscattering interferometry. The disclosed methods can have very low detection limits and/or very low sample volume requirements. Also disclosed are various biosensor applications of the disclosed techniques. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
(FR) La présente invention concerne des procédés pour la mesure en solution libre d'interactions moléculaires par détection d'indice de réfraction autre que l'interférométrie de rétrodiffusion. Les procédés de l'invention peuvent avoir des limites de détection très faibles et/ou des besoins de volume d'échantillon très faibles. L'invention concerne en outre différentes applications de biocapteur des techniques de l'invention. Le présent abrégé est destiné à être un outil d'analyse pour des applications de recherche dans l'art particulier et n'est pas destiné à être une limitation de la présente invention.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3408649IL260837US20190033301