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1. (WO2017131175) PROCESSED FOOD AND PHARMACEUTICAL COMPOSITION HAVING WATERMELON SPROUT-DERIVED SUBSTANCES AS MAIN INGREDIENTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/131175 International Application No.: PCT/JP2017/002982
Publication Date: 03.08.2017 International Filing Date: 27.01.2017
IPC:
A61K 31/045 (2006.01) ,A23L 33/105 (2016.01) ,A61K 31/047 (2006.01) ,A61K 36/42 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
045
Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
[IPC code unknown for A23L 33/105]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
045
Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
047
having two or more hydroxy groups, e.g. sorbitol
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
42
Cucurbitaceae (Cucumber family)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
学校法人近畿大学 KINKI UNIVERSITY [JP/JP]; 大阪府東大阪市小若江3丁目4番1号 3-4-1, Kowakae, Higashiosaka City, Osaka 5778502, JP
株式会社萩原農場生産研究所 HAGIHARA FARM PRODUCTION INSTITUTE CO.,LTD. [JP/JP]; 奈良県磯城郡田原本町法貴寺955 955 Hokiji, Tawaramoto-cho, Shiki-gun, Nara 6360222, JP
Inventors:
伊藤 智広 ITOH Tomohiro; JP
橋詰 利治 HASHIZUME Toshiharu; JP
Agent:
廣幸 正樹 HIROKOH Masaki; JP
Priority Data:
2016-01572129.01.2016JP
Title (EN) PROCESSED FOOD AND PHARMACEUTICAL COMPOSITION HAVING WATERMELON SPROUT-DERIVED SUBSTANCES AS MAIN INGREDIENTS
(FR) ALIMENTS TRANSFORMÉS ET COMPOSITION PHARMACEUTIQUE PRÉSENTANT DES SUBSTANCES DÉRIVÉES DE GERMES DE PASTÈQUE EN TANT QU’INGRÉDIENTS PRINCIPAUX
(JA) スイカスプラウト由来物質を主成分とする加工食品と医薬組成物
Abstract:
(EN) Drugs called molecularly targeted agents are being developed which act on signal transmission pathways in cells. However, the side effects cannot be said to be a low burden on patients. Accordingly, there is still demand for substances which exhibit a significant cancer cell growth-inhibiting effect, and few side effects, as health foods and pharmaceutical compositions. The hexane extraction fraction of watermelon sprouts has an effect of specifically inhibiting cancer cell growth. The main causes of this effect are understood to be phytol and lutein. Accordingly, a processed food and a pharmaceutical composition which have these as main ingredients can provide anticancer action with no side effects.
(FR) Les médicaments appelés agents à ciblage moléculaire développés actuellement agissent sur les voies de transmission de signaux dans des cellules. Toutefois, les effets secondaires ne peuvent pas être considérés comme légers pour les patients. En conséquence, il existe toujours une demande pour des substances présentant un important effet d'inhibition de la croissance de cellules cancéreuses et peu d'effets secondaires utilisées dans des aliments naturels et dans des compositions pharmaceutiques. La fraction d'extraction par hexane de germes de pastèque a un effet d'inhibition spécifique sur la croissance de cellules cancéreuses. Les principales causes de cet effet sont supposées être dues au phytol et à la xanthophylle. En conséquence, un aliment transformé et une composition pharmaceutique présentant ces derniers comme ingrédients principaux peuvent fournir une action anticancéreuse sans effets secondaires.
(JA) 分子標的剤と呼ばれる細胞中の信号伝達経路に作用する薬剤が開発されている。しかし、その副作用は患者にとっては負担が軽いとはいえない。したがって、副作用が少なく、癌細胞の増殖抑制効果の大きな物質は、健康食品や医薬組成物として依然として要望されている。 スイカスプラウトのヘキサン抽出画分には、特異的に癌細胞の細胞増殖を阻害する効果があり、その効果の主たる原因は、フィトールとルテインであることがわかった。これらを主成分とする加工食品や医薬組成物は、副作用のない抗癌作用を提供することができる。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
JPWO2017131175CN108601756