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1. (WO2017131034) TRANSDERMAL ABSORPTION PHARMACEUTICAL-PREPARATION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/131034 International Application No.: PCT/JP2017/002553
Publication Date: 03.08.2017 International Filing Date: 25.01.2017
IPC:
A61K 47/34 (2017.01) ,A61K 9/70 (2006.01) ,A61K 31/138 (2006.01) ,A61K 31/216 (2006.01) ,A61K 31/27 (2006.01) ,A61K 47/32 (2006.01) ,A61K 47/38 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
34
Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
70
Web, sheet or filament bases
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
13
Amines, e.g. amantadine
135
having aromatic rings, e.g. methadone
138
Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
216
of acids having aromatic rings, e.g. benactizyne, clofibrate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
27
of carbamic or thiocarbamic acids, e.g. meprobamate, carbachol, neostigmine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
32
Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
38
Cellulose; Derivatives thereof
Applicants:
久光製薬株式会社 HISAMITSU PHARMACEUTICAL CO., INC. [JP/JP]; 佐賀県鳥栖市田代大官町408番地 408, Tashirodaikan-machi, Tosu-shi, Saga 8410017, JP
Inventors:
天野 智史 AMANO Satoshi; JP
竹内 昭雄 TAKEUCHI Akio; JP
小林 弘明 KOBAYASHI Hiroaki; JP
黒川 隆夫 KUROKAWA Takao; JP
山▲崎▼ 真美子 YAMAZAKI Mamiko; JP
栗林 満 KURIBAYASHI Mitsuru; JP
本村 啓太 MOTOMURA Keita; JP
Agent:
長谷川 芳樹 HASEGAWA Yoshiki; JP
清水 義憲 SHIMIZU Yoshinori; JP
木元 克輔 KIMOTO Kosuke; JP
Priority Data:
2016-01417028.01.2016JP
Title (EN) TRANSDERMAL ABSORPTION PHARMACEUTICAL-PREPARATION
(FR) PRÉPARATION PHARMACEUTIQUE POUR ABSORPTION TRANSDERMIQUE
(JA) 経皮吸収製剤
Abstract:
(EN) Disclosed is a transdermal absorption pharmaceutical-preparation comprising: a drug reservoir layer having a first and a second primary surface and containing a drug; an adhesive agent layer disposed on the first primary surface of the drug reservoir layer and containing a silicone adhesive agent which includes a polyorganosiloxane; and a support formed such as to cover the side surfaces and the second primary surface of the drug reservoir layer. The silicon adhesive agent content is 20 mass% or greater relative to the total mass of the adhesive layer, and the moisture permeability of the transdermal absorption pharmaceutical-preparation overall is 20 g/m2·24hr to 314 g/m2·24 hr.
(FR) L'invention concerne une préparation pharmaceutique pour absorption transdermique comprenant : une couche réservoir de médicament comprenant des première et seconde surfaces primaires et contenant un médicament ; une couche d'agent adhésif disposée sur la première surface primaire de la couche réservoir de médicament et contenant un agent adhésif de silicone qui comprend un polyorganosiloxane ; et un support formé de façon à recouvrir les surfaces latérales et la seconde surface primaire de la couche réservoir de médicament. La teneur en agent adhésif de silicium est supérieure ou égale à 20 % en masse par rapport à la masse totale de la couche adhésive, et la perméabilité à l'humidité de la préparation pharmaceutique pour absorption transdermique globale est comprise entre 20 g/m2·par 24 h et 314 g/m2·par 24 h.
(JA) 第1及び第2の主面を有し、薬物を含有する薬物貯留層と、上記薬物貯留層の上記第1の主面側に設けられ、ポリオルガノシロキサンを含むシリコーン粘着剤を含有する粘着剤層と、上記薬物貯留層の側面及び上記第2の主面を覆うように形成される支持体と、を備える経皮吸収製剤であって、上記シリコーン粘着剤の含有量が、前記粘着剤層の全質量に対して20質量%以上であり、経皮吸収製剤全体としての透湿度が20g/m・24hr以上、314g/m・24hr以下である、経皮吸収製剤を開示する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)