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1. WO2017129645 - COMPOSITIONS COMPRISING 2FL AND LNnT TO CONTROL FOOD INTAKE AND GROWTH IN INFANTS OR YOUNG CHILDREN

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Claims

1 . Nutritional composition comprising at least one fucosylated oligosaccharide and at least one N-acetylated oligosaccharide, for use in reducing and/or controlling food intake in an infant or a young child.

2. Nutritional composition comprising at least one fucosylated oligosaccharide and at least one N-acetylated oligosaccharide, for use in promoting a healthy growth in an infant or a young child.

3. Nutritional composition for use according to any one of the preceding claims wherein the fucosylated oligosaccharide is selected from the list consisting of 2'-fucosyllactose, 3'fucosyllactose, difucosyllactose, lacto-N-fucopentaose I, lacto-N-fucopentaose II, lacto-N-fucopentaose III, lacto-N-fucopentaose V, lacto-N-fucohexaose, lacto-N-difucohexaose I, fucosyllacto-N-hexaose, fucosyllacto-N-neohexaose I, fucosyllacto-N-neohexaose II, difucosyllacto-N-hexaose I, difucosyllacto-N-neohexaose I, difucosyllacto-N-neohexaose II, fucosyl-para-Lacto-N-hexaose, and any combination thereof.

4. Nutritional composition for use according to any one of the preceding claims, wherein the fucosylated oligosaccharide comprises a 2' fucosyl-epitope.

5. Nutritional composition for use according to any one of the preceding claims, wherein the fucosylated oligosaccharide is 2'-fucosyllactose (2'FL).

6. Nutritional composition for use according to any one of the preceding claims, wherein the N-acetylated oligosaccharide is selected from the list consisting of lacto-N-tetraose (LNT), lacto-N-neotetraose (LNnT) and any combination thereof.

7. Nutritional composition for use according to any one of the preceding claims, wherein the N-acetylated oligosaccharide is lacto-N-neotetraose (LNnT), para-lacto-N-neohexaose (para-LNnH) or any combination thereof, preferably wherein the N-acetylated oligosaccharide is lacto-N-neotetraose (LNnT).

8. Nutritional composition for use according to any one of the preceding claims, comprising 2'-fucosyllactose (2'FL) and lacto-N-neotetraose (LNnT), or comprising an oligosaccharide mixture consisting of 2'-fucosyllactose (2'FL) and lacto-N-neotetraose (LNnT).

9. Nutritional composition for use according to any one of the preceding claims wherein the fucosylated oligosaccharide(s):N-acetylated oligosaccharide(s) weight ratio is from 1 :10 to 12:1 , such as from 1 :2 to 2:1.

10. Nutritional composition for use according to any one of the preceding claims, wherein the at least one fucosylated oligosaccharide and at least one N-acetylated oligosaccharide are present in a total amount of from 0.1 to 10 wt%, such as from 0.5 to 7 wt% or from 1 to 5 wt% of the nutritional composition.

1 1 . Nutritional composition for use according to any one of the preceding claims, comprising at least another oligosaccharide(s) and/or fiber(s) and/or precursor(s) of human milk oligosaccharide(s) selected from the list consisting of galacto-oligosaccharides (GOS), fructo-oligosaccharides (FOS), xylooligosaccharides (XOS), inulin, polydextrose, sialylated oligosaccharides, sialic acid, fucose and any combination thereof.

12. Nutritional composition for use according to any one of the preceding claims, said composition further comprising at least one probiotic in an amount of from 103 to 1012 cfu/g of said composition (dry weight).

13. Nutritional composition for use according to any one of the preceding claims, wherein said nutritional composition is an infant formula, a starter infant formula, a follow-on or follow-up infant formula, a baby food, an infant cereal composition, a fortifier or a supplement.

14. Nutritional composition for use according to any one of the preceding claims wherein said infants or young children are infants or young children at risk and/or in need.

15. Nutritional composition for use according to any claim 14 wherein said infants or young children meet at least one of the following criteria:

- they have difficulties with controlling their food intake or they have an abnormal food intake such as:

i) they eat more than other infants or young children of the same age and of the same size; and/or

ii) they have an altered perception of satiety; and/or

- they have an excessive weight gain during the first few months of life.

16. Nutritional composition for use according to any one of the preceding claims by increasing the satiety responsiveness in said infant or young child.

17. Nutritional composition for use according to any one of the preceding claims by increasing the colonic propionate production in said infant or young child.

18. Nutritional composition for use according to any one of the preceding claims to avoid excessive weight gain and/or to promote lean mass increase in an infant or young child.

19. Nutritional composition according to any one of the preceding claims for increasing the satiety responsiveness in an infant or young child.