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1. (WO2017129585) PHARMACEUTICAL COMPOSITION COMPRISING BISPECIFIC ANTIBODY CONSTRUCTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/129585 International Application No.: PCT/EP2017/051486
Publication Date: 03.08.2017 International Filing Date: 25.01.2017
IPC:
C07K 16/28 (2006.01) ,A61K 39/395 (2006.01) ,A61K 47/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
Applicants:
AMGEN RESEARCH (MUNICH) GMBH [DE/DE]; Staffelseestrasse 2 81477 Munich, DE
AMGEN INC. [US/US]; One Amgen Center Drive Thousand Oaks, California 91320-1799, US
Inventors:
KANAPURAM, Sekhar; US
LATYPOV, Ramil; US
THANGARAJ, Balakumar; US
POMPE, Cornelius; DE
Agent:
WEINZIERL, Gerhard Dr.; DE
SCHIWECK, Wolfram Dr.; DE
KOCH, Andreas Dr.; DE
Priority Data:
62/286,55225.01.2016US
Title (EN) PHARMACEUTICAL COMPOSITION COMPRISING BISPECIFIC ANTIBODY CONSTRUCTS
(FR) COMPOSITION PHARMACEUTIQUE COMPRENANT DES CONSTRUCTIONS D'ANTICORPS BI-SPÉCIFIQUES
Abstract:
(EN) The present invention provides novel and stable pharmaceutical compositions comprising bispecific single chain antibody constructs, cyclodextrins and a buffer.
(FR) La présente invention concerne de nouvelles compositions pharmaceutiques stables comprenant des constructions d'anticorps bi-spécifiques à chaîne unique, ainsi que des cyclodextrines et un tampon.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
UAa201808908AU2017213050CA3011082SG11201805738QMYPI 2018702559KR1020180100439
ID2018/11887EP3408295IL260753CN109071657BR112018014986PH1/2018/501419
EA201891694CR20180408