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1. (WO2017128096) RADIX ASTRAGALI GLYCOPROTEIN AND PREPARATION METHOD AND USE THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/128096 International Application No.: PCT/CN2016/072263
Publication Date: 03.08.2017 International Filing Date: 26.01.2016
IPC:
A61K 38/16 (2006.01) ,A61K 36/481 (2006.01) ,C07K 14/415 (2006.01) ,A61P 19/02 (2006.01) ,A61P 37/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
48
Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
481
Astragalus (milkvetch)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
415
from plants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19
Drugs for skeletal disorders
02
for joint disorders, e.g. arthritis, arthrosis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
Applicants:
山西中医学院 SHANXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE [CN/CN]; 中国山西省晋中市 山西省高校新区大学街121号 121# College Street, University Area Jinzhong, Shanxi 030600, CN
Inventors:
薛慧清 XUE, Huiqing; CN
冯前进 FENG, Qianjin; CN
周然 ZHOU, Ran; CN
任晋宏 REN, Jinhong; CN
刘晔 LIU, Ye; CN
王永辉 WANG, Yonghui; CN
李敏 LI, Min; CN
白承之 BAI, Chengzhi; CN
李安平 LI, Anping; CN
李明花 LI, Minghua; CN
秦文杰 QIN, Wenjie; CN
Agent:
北京太兆天元知识产权代理有限责任公司 IPROPERTYONE INTELLECTUAL PROPERTY CO., LTD.; 中国北京市 海淀区马甸东路19号金澳国际大厦1609室 Room 1609, Jin'ao International Buidling No.19, Madian East Road, Haidian District Beijing 100088, CN
Priority Data:
Title (EN) RADIX ASTRAGALI GLYCOPROTEIN AND PREPARATION METHOD AND USE THEREOF
(FR) GLYCOPROTÉINE DE RACINE D'ASTRAGALUS PROPINQUUS, ET PROCÉDÉ DE PRÉPARATION ET UTILISATION DE CETTE DERNIÈRE
(ZH) 一种黄芪糖蛋白及其制备方法和用途
Abstract:
(EN) Disclosed are a radix astragali glycoprotein and a preparation method and a use of the radix astragali glycoprotein in the preparation of a medicine for treating rheumatoid arthritis or autoimmune encephalomyelitis, wherein the radix astragali glycoprotein is made from the following glycoprotein separation and purification steps: medical material treatment, total protein extraction and anion exchange chromatography and purification, hydrophobic chromatography and purification, and gel filtration chromatography, etc.
(FR) L'invention concerne une glycoprotéine de la racine d'Astragalus propinquus, et un procédé de préparation et une utilisation de la glycoprotéine de la racine d'Astragalus propinquus dans la préparation d'un médicament pour traiter la polyarthrite rhumatoïde ou l'encéphalomyélite autoimmune, la glycoprotéine de la racine d'Astragalus propinquus étant préparée en suivant les étapes de séparation et de purification de la glycoprotéine suivantes : traitement du matériau médical, extraction des protéines totales et chromatographie par échange d'anions et purification, chromatographie hydrophobe et purification, et chromatographie par filtration sur gel, etc.
(ZH) 一种黄芪糖蛋白及其制备方法和该黄芪糖蛋白在制备用于治疗类风湿性关节炎或自身免疫性脑脊髓炎的药剂中的用途,其中该黄芪糖蛋白由药材处理、总蛋白提取以及阴离子交换层析纯化、疏水性层析纯化、凝胶过滤层析等糖蛋白分离纯化步骤制成。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)