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1. (WO2017118915) AMORPHOUS AND CRYSTALLINE SOLID FORMS OF LUMACAFTOR OR ITS COMPLEX AND PREPARATIVE PROCESSES THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/118915 International Application No.: PCT/IB2017/050003
Publication Date: 13.07.2017 International Filing Date: 03.01.2017
IPC:
A61K 31/00 (2006.01) ,C07D 405/12 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
405
Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
Applicants:
DR. REDDY'S LABORATORIES LIMITED [IN/IN]; 8-2-337, Road No. 3, Banjara Hills Hyderabad 500034, IN
Inventors:
BAIG, Mohammed Azeezulla; IN
CHAKKA, Ramesh; IN
VYALA, Sunitha; IN
PATHIVADA, Deepika; IN
CHENNURU, Ramanaiah; IN
PEDDY, Vishweshwar; IN
Priority Data:
20164100011804.01.2016IN
20164100863911.03.2016IN
20164101117430.03.2016IN
Title (EN) AMORPHOUS AND CRYSTALLINE SOLID FORMS OF LUMACAFTOR OR ITS COMPLEX AND PREPARATIVE PROCESSES THEREOF
(FR) FORMES SOLIDES AMORPHES ET CRISTALLINES DU LUMACAFTOR OU SON COMPLEXE ET LEURS PROCÉDÉS DE PRÉPARATION
Abstract:
(EN) Aspects of the present application relate to Amorphous Lumacaftor, its amorphous solid dispersion and pharmaceutical compositions thereof. Further aspects relate to processes for the preparation of crystalline and amorphous Lumacaftor and solid dispersions thereof. Other aspects of the present application include a complex of Lumacaftor and Ivacaftor, its crystalline and amorphous phase, their preparative processes and pharmaceutical compositions thereof.
(FR) L'invention concerne, dans certains aspects, le lumacaftor amorphe, sa dispersion solide amorphe et des compositions pharmaceutiques associées. D'autres aspects concernent des procédés de préparation des formes amorphes et cristallines du lumacaftor et des dispersions solides associées. D'autres aspects de la présente invention comprennent un complexe du lumacaftor et de l'ivacaftor, sa phase cristalline et amorphe, des procédés de préparation associés et des compositions pharmaceutiques associées.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)