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1. (WO2017112803) NOVEL ANTI-MMP16 ANTIBODIES AND METHODS OF USE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/112803 International Application No.: PCT/US2016/068103
Publication Date: 29.06.2017 International Filing Date: 21.12.2016
IPC:
C07K 16/40 (2006.01) ,A61K 31/551 (2006.01) ,A61K 47/68 (2017.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
40
against enzymes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
55
having seven-membered rings, e.g. azelastine, pentylenetetrazole
551
having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
[IPC code unknown for A61K 47/68]
Applicants:
ABBVIE STEMCENTRX LLC [US/US]; 1 North Waukegan Road North Chicago, Illinois 60064, US
Inventors:
ROY, Somdutta; US
WILLIAMS, Samuel A.; US
DYLLA, Scott J.; US
HUANG, Zhao; US
SAUNDERS, Laura; US
LIU, David; US
FRANKLIN, Casey; US
COELHO, David; US
Agent:
MEIGS, Julie Broadus; US
CAWLEY, JR., Thomas; US
RAY, Denise M.; US
Priority Data:
62/270,84622.12.2015US
62/433,75913.12.2016US
Title (EN) NOVEL ANTI-MMP16 ANTIBODIES AND METHODS OF USE
(FR) NOUVEAUX ANTICORPS ANTI-MMP16 ET MÉTHODES D'UTILISATION
Abstract:
(EN) Provided are novel anti-MMP16 antibodies and antibody drug conjugates, and methods of using such anti-MMP16 antibodies and antibody drug conjugates to treat cancer.
(FR) L'invention concerne de nouveaux anticorps anti-MMP16 et des conjugués anticorps-médicaments, ainsi que des méthodes d'utilisation de tels anticorps anti-MMP16 et des conjugués anticorps-médicaments dans le traitement du cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU2016377669CA3009484CN108431043EP3394106BR112018012884US20190022242