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1. (WO2017111087) MONOFLUOROPHOSPHATE ESTER SALT, METHOD FOR PRODUCING SAME, AND FLUORINE ION-RELEASING COMPOSITION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/111087 International Application No.: PCT/JP2016/088497
Publication Date: 29.06.2017 International Filing Date: 22.12.2016
IPC:
C07F 9/14 (2006.01) ,A61K 8/69 (2006.01) ,A61K 31/661 (2006.01) ,A61K 33/16 (2006.01) ,A61P 1/02 (2006.01) ,A61Q 11/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9
Compounds containing elements of the 5th Group of the Periodic System
02
Phosphorus compounds
06
without P-C bonds
08
Esters of oxyacids of phosphorus
09
Esters of phosphoric acids
14
containing P-halide groups
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
69
containing fluorine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
66
Phosphorus compounds
661
Phosphorus acids or esters thereof not having P-C bonds, e.g. fosfosal, dichlorvos, malathion
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
16
Fluorine compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
02
Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
11
Preparations for care of the teeth, of the oral cavity or of dentures, e.g. dentifrices or toothpastes; Mouth rinses
Applicants:
ステラケミファ株式会社 STELLA CHEMIFA CORPORATION [JP/JP]; 大阪府大阪市中央区淡路町3丁目6番3号 3-6-3, Awaji-machi Chuo-ku Osaka-shi Osaka 5410047, JP
Inventors:
坂口 紀敬 SAKAGUCHI Toshitaka; JP
桂 静郁 KATSURA Yoshifumi; JP
山本 雅士 YAMAMOTO Masashi; JP
西田 哲郎 NISHIDA Tetsuo; JP
Agent:
小山 靖 KOYAMA Yasushi; JP
Priority Data:
2015-25284525.12.2015JP
Title (EN) MONOFLUOROPHOSPHATE ESTER SALT, METHOD FOR PRODUCING SAME, AND FLUORINE ION-RELEASING COMPOSITION
(FR) SEL ESTER MONOFLUOROPHOSPHATE, SON PROCÉDÉ DE PRODUCTION, ET COMPOSITION DE LIBÉRATION D’IONS FLUOR
(JA) モノフルオロリン酸エステル塩、その製造方法及びフッ素イオン放出性組成物
Abstract:
(EN) [Problem] To provide: a monofluorophosphate ester salt capable of the sustained release of fluorine ions at a significant amount of release; a method for producing the monofluorophosphate ester salt; and a fluorine ion-releasing composition. [Solution] The monofluorophosphate ester salt of the present invention is characterized by being represented by chemical formula (1). (Mn+ represents any one species selected from the group consisting of a hydrogen ion, alkali metal ion, alkaline-earth metal ion, transition metal ion, rare-earth element ion, zinc ion, aluminum ion, gallium ion, indium ion, germanium ion, tin ion, lead ion, and onium ion. R1 represents a hydrocarbon group that has 1 to 20 carbons or a hydrocarbon group that has 1 to 20 carbons and that has at least one of any of a halogen atom, a heteroatom, and an unsaturated bond. n represents the valence.)
(FR) Le problème à résoudre par la présente invention consiste à préparer : un sel ester monofluorophosphate capable de soutenir la libération d’ions fluor à une quantité significative de libération ; un procédé de production de sel ester monofluorophosphate ; et une composition de libération d’ions fluor. Le sel ester monofluorophosphate de la présente invention est caractérisé en ce qu’il est représenté par la formule chimique (1). (Mn+ représente n’importe quelle espèce sélectionnée dans le groupe constitué d’un ion hydrogène, d’un ion de métal alcalin, d’un ion de métal alcalino-terreux, d’un ion de métal de transition, d’un ion d’élément de terres rares, d’un ion zinc, d’un ion aluminium, d’un ion gallium, d’un ion indium, d’un ion germanium, d’un ion étain, d’un ion plomb, et d’un ion onium. R1 représente un groupe hydrocarbure qui possède de 1 à 20 atomes de carbone ou un groupe hydrocarbure qui possède de 1 à 20 atomes de carbone et qui possède au moins l’un de n’importe lequel d’un atome d’halogène, d’un hétéroatome, et d’une liaison insaturée. n représente la valence.)
(JA) 【課題】フッ素イオンを有意な放出量で持続して放出させることが可能なモノフルオロリン酸エステル塩、その製造方法及びフッ素イオン放出性組成物を提供する。 【解決手段】本発明のモノフルオロリン酸エステル塩は、下記化学式(1)で表されることを特徴とする。 (但し、前記Mn+は、水素イオン、アルカリ金属イオン、アルカリ土類金属イオン、遷移金属イオン、希土類元素イオン、亜鉛イオン、アルミニウムイオン、ガリウムイオン、インジウムイオン、ゲルマニウムイオン、スズイオン、鉛イオン及びオニウムイオンからなる群より選ばれる何れか1種を表す。前記Rは、炭素数が1~20の炭化水素基、又は炭素数が1~20の範囲であって、ハロゲン原子、ヘテロ原子若しくは不飽和結合の少なくとも何れか1つを有する炭化水素基を表す。前記nは価数を表す。)
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)