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1. (WO2017100376) PROMOTERS FROM CORYNEBACTERIUM GLUTAMICUM

Pub. No.:    WO/2017/100376    International Application No.:    PCT/US2016/065464
Publication Date: Fri Jun 16 01:59:59 CEST 2017 International Filing Date: Thu Dec 08 00:59:59 CET 2016
IPC: C12N 15/77
Applicants: ZYMERGEN INC.
Inventors: SERBER, Zach
GORA, Katherine G.
MANCHESTER, Shawn P.
Title: PROMOTERS FROM CORYNEBACTERIUM GLUTAMICUM
Abstract:
Provided are native promoters comprising polynucleotides isolated from Corynebacterium glutamicum, and mutant promoters derived therefrom, which may be used to regulate, i.e., either increase or decrease, gene expression. Also provided are promoter ladders comprising a plurality of the promoters having incrementally increasing promoter activity. Also provided are host cells and recombinant vectors comprising the promoters, and methods of expressing genes of interest and producing biomolecules using the host cells.