Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2017097946) NOVEL PROTEINS SPECIFIC FOR CALCITONIN GENE-RELATED PEPTIDE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/097946 International Application No.: PCT/EP2016/080353
Publication Date: 15.06.2017 International Filing Date: 09.12.2016
IPC:
C07K 14/47 (2006.01) ,A61K 38/22 (2006.01) ,C12N 5/00 (2006.01) ,C07K 16/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
Applicants:
PIERIS PHARMACEUTICALS GMBH [DE/DE]; Lise-Meitner-Strasse 30 85354 Freising-Weihenstephan, DE
Inventors:
KUBOTA, Kazufumi; JP
MAKINO, Mitsuhiro; JP
TAKAHASHI, Sakiko; JP
HASHIMOTO, Ryuji; JP
TAKAHASHI, Tohru; JP
OTOYO, Mamoru; JP
MATSCHINER, Gabriele; DE
ROTHE, Christine; DE
WIEDENMANN, Alexander; DE
BEL AIBA, Rachida Siham; DE
HINNER, Marlon; DE
ALLERSDORFER, Andrea; DE
LUNDE, Bradley; DE
Agent:
WEINZIERL, Gerhard; DE
SCHIWECK, Wolfram Dr.; DE
KOCH, Andreas Dr.; DE
Priority Data:
62/265,79210.12.2015US
Title (EN) NOVEL PROTEINS SPECIFIC FOR CALCITONIN GENE-RELATED PEPTIDE
(FR) NOUVELLES PROTÉINES SPÉCIFIQUES DU PEPTIDE LIÉ AU GÈNE DE LA CALCITONINE
Abstract:
(EN) The present disclosure provides hNGAL muteins that bind CGRP and can be used in various application including pharmaceutical applications, for example, migraine. The present disclosure also concerns methods of making one or more muteins described herein as well as compositions and combinations comprising one or more of such muteins. The present disclosure further relates to nucleic acid molecules encoding such muteins and to methods for generation of such muteins and nucleic acid molecules. In addition, the application discloses therapeutic and/or diagnostic uses of these muteins as well as compositions and combinations comprising one or more of such muteins.
(FR) La présente invention concerne des mutéines hNGAL qui se lient à CGRP et peuvent être utilisées dans diverses applications, y compris des applications pharmaceutiques, par exemple, contre la migraine. La présente invention concerne également des procédés de fabrication d'une ou de plusieurs mutéines de l'invention, ainsi que des compositions et des combinaisons comprenant une ou plusieurs de ces mutéines. De plus, l'invention concerne des molécules d'acide nucléique codant pour lesdites mutéines, et des procédés de production de ces mutéines et molécules d'acide nucléique. L'invention concerne en outre des utilisations thérapeutiques et/ou diagnostiques de ces mutéines, ainsi que des compositions et des combinaisons comprenant une ou plusieurs de ces mutéines.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU2016367207CA3006914IN201817021488EP3387009CN109071621