Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2017097891) CRYSTALLINE ERAVACYCLINE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/097891 International Application No.: PCT/EP2016/080232
Publication Date: 15.06.2017 International Filing Date: 08.12.2016
IPC:
C07D 295/15 (2006.01) ,A61K 31/40 (2006.01) ,A61P 31/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
295
Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
04
with substituted hydrocarbon radicals attached to ring nitrogen atoms
14
substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
145
with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
15
to an acyclic saturated chain
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
Applicants:
SANDOZ AG [CH/CH]; Lichtstrasse 35 4056 Basel, CH
Inventors:
LENGAUER, Hannes; AT
Agent:
OSER, Andreas; DE
ENGLMEIER, Ludwig; DE
Priority Data:
15199394.610.12.2015EP
Title (EN) CRYSTALLINE ERAVACYCLINE
(FR) ÉRAVACYCLINE CRISTALLINE
Abstract:
(EN) The invention relates to crystalline eravacycline and to a process for its preparation. Furthermore, the invention relates to the use of crystalline eravacycline for the preparation of a pharmaceutical composition. The pharmaceutical composition of the present invention can be used as a medicament, in particular for treatment and/or prevention of bacterial infections such as caused by Gram negative pathogens, in particular by multidrug resistant Gram negative pathogens. The pharmaceutical composition of the present invention can thus be used as a medicament for e.g. the treatment of complicated intra-abdominal and urinary tract infections.
(FR) La présente invention concerne une éravacycline cristalline et son procédé de préparation. En outre, l'invention concerne l'utilisation d'éravacycline cristalline dans la préparation d'une composition pharmaceutique. La composition pharmaceutique de la présente invention peut être utilisée comme médicament, en particulier pour le traitement et/ou la prévention des infections bactériennes telles que celles causées par les pathogènes à Gram négatif, en particulier par les pathogènes à Gram négatif multirésistants. La composition pharmaceutique de la présente invention peut ainsi être utilisée comme médicament destiné par exemple au traitement des infections intra-abdominales et du tractus urinaire compliquées.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)