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1. (WO2017097688) ENCAPSULATING AGENT WITH IMPROVED PROPERTIES ADAPTED FOR CELL ENCAPSULATION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/097688 International Application No.: PCT/EP2016/079707
Publication Date: 15.06.2017 International Filing Date: 05.12.2016
IPC:
A61K 9/16 (2006.01) ,A61K 35/12 (2015.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
Applicants:
LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST) [LU/LU]; 5, avenue des Hauts-Fourneaux 4362 Esch-sur-Alzette, LU
Inventors:
SCHLEEH, Thomas; DE
Agent:
LECOMTE & PARTNERS; P.O. Box 1623 1016 Luxembourg, LU
Priority Data:
LU9289508.12.2015LU
Title (EN) ENCAPSULATING AGENT WITH IMPROVED PROPERTIES ADAPTED FOR CELL ENCAPSULATION
(FR) AGENT D’ENCAPSULATION AYANT DES PROPRIÉTÉS AMÉLIORÉES ADAPTÉ POUR L’ENCAPSULATION DE CELLULES
Abstract:
(EN) The invention is directed to a three-dimensional polymer network for encapsulating a pharmaceutical ingredient, said polymer network comprising (a) at least one first polymer; and (b) at least one cross-linking agent. Said three-dimensional polymer network is remarkable in that said at least one first polymer comprises a first polyuronate derivative, said first polyuronate derivative being modified with a hydrophobic moiety; and in that said at least one cross-linking agent is calcium chloride and/or a cyclodextrin derivative.
(FR) La présente invention concerne un réseau de polymère tridimensionnel pour encapsuler une substance pharmaceutique, ledit réseau de polymère comprenant (a) au moins un premier polymère ; et (b) au moins un agent de réticulation. Ledit réseau de polymères tridimensionnels et remarquables en ce que le dit au moins un premier polymère comprend un premier dérivé de polyuronate, ledit premier dérivé de polyuronate étant modifié par uun fragment hydrophobe ; et en ce que ledit au moins un agent de réticulation est le chlorure de calcium et/ou un dérivé de cyclodextrine.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3386486US20190038567