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1. (WO2017096530) DECOQUINATE SOLID DISPERSION, METHOD FOR PREPARING SAME AND USE THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/096530 International Application No.: PCT/CN2015/096689
Publication Date: 15.06.2017 International Filing Date: 08.12.2015
IPC:
A61K 31/47 (2006.01) ,A61K 47/00 (2006.01) ,A61K 47/30 (2006.01) ,A61K 47/32 (2006.01) ,A61K 47/34 (2017.01) ,A61K 9/00 (2006.01) ,A61P 33/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
47
Quinolines; Isoquinolines
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
32
Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
34
Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
33
Antiparasitic agents
02
Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
06
Antimalarials
Applicants:
广州蓝亮医药科技有限公司 BLUELIGHT PHARMATECH CO., LTD [CN/CN]; 中国广东省广州市 中新广州知识城九佛建设路115号397房 Room 397, No. 115, Jiufo Jianshe Road, Zhongxin Guangzhou Knowledge City Guangzhou, Guangdong 510530, CN
Inventors:
王洪星 WANG, Hongxing; CN
范银洲 FAN, Yinzhou; CN
陈雪清 CHEN, Xueqing; CN
陈小平 CHEN, Xiaoping; CN
Agent:
北京品源专利代理有限公司 BEYOND ATTORNEYS AT LAW; 中国北京市 海淀区莲花池东路39号西金大厦6层 F6, Xijin Centre 39 Lianhuachi East Rd., Haidian District Beijing 100036, CN
Priority Data:
Title (EN) DECOQUINATE SOLID DISPERSION, METHOD FOR PREPARING SAME AND USE THEREOF
(FR) DISPERSION SOLIDE DE DÉCOQUINATE, PROCÉDÉ DE PRÉPARATION ET UTILISATION DE CETTE DERNIÈRE
(ZH) 癸氧喹酯固体分散体、其制备方法和用途
Abstract:
(EN) A hot-melt extruded solid dispersion composition, a method for preparing same and a use of the composition in preparation of medicines for preventing and/or treating diseases caused by Plasmodium. The composition comprises, according to percentage by weight, 5%-30% of decoquinate, 60%-90% of macromolecular carrier material, and 0%-10% of surfactant. The method for preparing the composition comprises a step of hot-extruding the position at a hot-melting temperature.
(FR) L'invention concerne une composition d'une dispersion solide extrudée à chaud, un procédé de préparation de cette dernière, et une utilisation de la composition dans la préparation de médicaments pour prévenir et/ou traiter des maladies causées par le Plasmodium. La composition comprend, en pourcentage en poids, 5 % à 30 % de décoquinate, 60 % à 90 % de matériau de support macromoléculaire, et 0 % à 10 % d'un tensioactif. Le procédé de préparation de la composition consiste à extruder la position à chaud à une température de fusion à chaud.
(ZH) 一种热熔挤出固体分散体组合物及其制备方法和该组合物在制备用于预防和/或治疗由疟原虫引起的疾病的药剂中的用途。按重量百分比计,该组合物包括癸氧喹酯5%-30%、高分子载体材料60%-90%和表面活性剂0%-10%。组合物的制备方法包括在热熔温度下热挤出该组合物的步骤。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)
Also published as:
CN107427504US20170360708EP3388065GB2561497IN201827025383