Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2017096484) USE OF CRANBERRY DERIVED PHENOLIC COMPOUNDS AS ANTIBIOTIC SYNERGIZING AGENT AGAINST PATHOGENIC BACTERIA
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/096484 International Application No.: PCT/CA2016/051447
Publication Date: 15.06.2017 International Filing Date: 09.12.2016
IPC:
A61K 36/45 (2006.01) ,A61K 31/505 (2006.01) ,A61K 31/635 (2006.01) ,A61K 31/04 (2006.01) ,C07D 239/49 (2006.01) ,C07D 261/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
45
Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
63
Compounds containing para-N-benzene- sulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonohydrazide
635
having a heterocyclic ring, e.g. sulfasalazine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
04
Nitro compounds
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
239
Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
02
not condensed with other rings
24
having three or more double bonds between ring members or between ring members and non-ring members
28
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
46
Two or more oxygen, sulfur or nitrogen atoms
48
Two nitrogen atoms
49
with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
261
Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
02
not condensed with other rings
06
having two or more double bonds between ring members or between ring members and non-ring members
10
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
14
Nitrogen atoms
16
Benzene-sulfonamido isoxazoles
Applicants:
THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY [CA/CA]; 845 Sherbrooke Street Montreal, Québec H3A 0G4, CA
Inventors:
TUFENKJI, Nathalie; CA
MAISURIA, Vimal Bharatbhai; CA
Agent:
NORTON ROSE FULBRIGHT CANADA LLP, S.E.N.R.C.L., S.R.L.; Suite 2500 1 Place Ville-Marie Montreal, Québec H3B 1R1, CA
Priority Data:
62/266,33411.12.2015US
62/366,66626.07.2016US
Title (EN) USE OF CRANBERRY DERIVED PHENOLIC COMPOUNDS AS ANTIBIOTIC SYNERGIZING AGENT AGAINST PATHOGENIC BACTERIA
(FR) UTILISATION DE COMPOSÉS PHÉNOLIQUES DÉRIVÉS DE CANNEBERGE EN TANT QU’AGENT DE SYNERGIE ANTIBIOTIQUE CONTRE DES BACTÉRIES PATHOGÈNES
Abstract:
(EN) This present disclosure relates to the use of a cranberry extract rich in proanthocyanidins as antibiotic synergizing agent to mitigate multidrug resistance and biofilm formation in different pathogenic bacteria. The synergistic combination of antibiotic and cranberry extract could treat bacterial infections using a lower dose of antibiotics to prevent biofilm formation and proliferation of microorganisms, with defined modes of action.
(FR) La présente invention concerne l'utilisation d'un extrait de canneberge riche en proanthocyanidines en tant qu’agent de synergie antibiotique permettant d’atténuer la résistance pléiotropique et la formation de biofilms dans différentes bactéries pathogènes. La combinaison synergique d'antibiotique et d’extrait de canneberge pourrait traiter des infections bactériennes à l'aide d'une dose plus faible d'antibiotiques pour empêcher la formation de biofilms et la prolifération de micro-organismes, selon des modes d'action définis.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3386526US20180360898CA3046254