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1. (WO2017096373) SYSTEMS AND METHODS FOR INTERFERENCE CORRECTION FROM HEMOGLOBIN VARIANTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/096373 International Application No.: PCT/US2016/064967
Publication Date: 08.06.2017 International Filing Date: 05.12.2016
IPC:
G01N 33/72 (2006.01) ,C07K 16/18 (2006.01) ,G01N 33/48 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
72
involving blood pigments, e.g. hemoglobin, bilirubin
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
Applicants:
POLYMER TECHNOLOGY SYSTEMS, INC. [US/US]; 7736 Zionsville Road Indianapolis, Indiana 46268, US
Inventors:
XIE, Charles Z.; US
KYUNG, Jane; US
NGUYEN, Tu-Anh; US
MENDOZA, Annie V.; US
MOSKOWITZ, Keith; US
Agent:
ZIEMIAN, Robert P.; US
NASH, William B.; US
MENCHER, Joseph R.; US
Priority Data:
62/263,47804.12.2015US
62/322,68714.04.2016US
Title (EN) SYSTEMS AND METHODS FOR INTERFERENCE CORRECTION FROM HEMOGLOBIN VARIANTS
(FR) SYSTÈMES ET PROCÉDÉS DE CORRECTION D'INTERFÉRENCES DE VARIANTES D'HÉMOGLOBINE
Abstract:
(EN) A system for determining a concentration of hemoglobin A1C includes a first lateral flow test strip, the first lateral flow test strip providing for a percent of HbA1C concentration; a second lateral flow test strip, the second lateral flow test strip providing for the total amount of hemoglobin; an antibody-microparticle stripe on each of the first and second lateral flow test strips; a conjugate stripe on each of the first and second lateral flow test strips; and a sample treatment buffer. The sample treatment buffer is strongly denaturing, and antibodies in the antibody-microparticle strip are covalently bound to microparticles.
(FR) La présente invention concerne un système servant à déterminer une concentration d'hémoglobine A1C qui comprend une première bande d'analyse d'écoulement latéral, ladite première bande d'analyse d'écoulement latéral permettant d'obtenir un pourcentage de concentration d'HbA1C ; une seconde bande d'analyse d'écoulement latéral, ladite seconde bande d'analyse d'écoulement latéral permettant d'obtenir la quantité totale d'hémoglobine ; une bande de microparticules-anticorps sur chacune des première et seconde bandes d'analyse d'écoulement latéral ; une bande conjuguée sur chacune des première et seconde bandes d'analyse d'écoulement latéral ; et un tampon de traitement d'échantillon. Ledit tampon de traitement d'échantillon est fortement dénaturant, et les anticorps présents dans la bande de microparticules-anticorps sont liés de manière covalente aux microparticules.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)