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1. (WO2017096270) METHODS FOR TREATING MITOCHONDRIAL DISEASES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2017/096270 International Application No.: PCT/US2016/064779
Publication Date: 08.06.2017 International Filing Date: 02.12.2016
IPC:
A61K 9/24 (2006.01) ,A61K 9/22 (2006.01) ,A61K 31/44 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
22
Sustained or differential release type
24
Layered or laminated unitary dosage forms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
22
Sustained or differential release type
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; Office of Technology Transfer 1111 Franklin Street, Twelth Floor Oakland, California 94607, US
Inventors:
CORTOPASSI, Gino; US
DATTA, Sandipan; US
YU, Alfred; US
Agent:
HAO, Joe C.; US
Priority Data:
62/262,79203.12.2015US
Title (EN) METHODS FOR TREATING MITOCHONDRIAL DISEASES
(FR) MÉTHODES DE TRAITEMENT DE MALADIES MITOCHONDRIALES
Abstract:
(EN) The present invention provides pharmaceutical compounds and methods for preventing, ameliorating, or treating a mitochondrial disease by administering such compounds to a subject in need thereof. In some cases, the subject suffers from a mitochondrial disease or is predisposed to having a mitochondrial disease. The mitochondrial disease includes those associated with impairments to mitochondrial oxidative phosphorylation that can lead to vision loss or blindness.
(FR) La présente invention concerne des composés pharmaceutiques et des méthodes destinées à prévenir, à atténuer ou à traiter une maladie mitochondriale par l'administration de tels composés à un sujet qui en a besoin. Dans certains cas, le sujet souffre d'une maladie mitochondriale ou est prédisposé à une maladie mitochondriale. La maladie mitochondriale inclut celles associées à des altérations de la phosphorylation oxydative mitochondriale qui peuvent conduire à une perte de la vue ou à la cécité.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)